Cat. No. | Product Name | Target | Signaling Pathways |
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T1767 |
BMH-21
BMH21 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
BMH-21 是一种小分子 DNA 嵌入剂,可结合核糖体 DNA 并抑制 RNA 聚合酶 I (Pol I) 转录,具有抗癌活性。 | |||
T33410 |
MitoNeoD
Mito Neo D,Mito-Neo-D,Mito Neo-D,Mito-NeoD |
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MitoNeoD is a novel mitochondria-targeted O2(⋅−) probe that can be used in vivo. It prevents DNA intercalation. MitoNeoD incorporates a carbon-deuterium bond, and enhances O2(⋅−) selectivity. | |||
T69283 | Amikhellin HCl | ||
Amikhellin HCl, an antimitotic drug, is a synthetic water-soluble derivative of khellin, an alkaloid extracted from seeds of Ammi Visnaga. Amikhellin has been used so far mostly as a vasodiator. Amikhellin binds to double-stranded DNA by an intercalation process. It inhibits the DNA-polymerase from murine sarcoma leukemia virus. | |||
T75336 |
TO-PRO 1
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TO-PRO 1, 一种DNA结合荧光染料, 通过附着于Feraheme (FH)纳米颗粒 (NP)表面实现荧光染料功能化的NP。该染料通过嵌入结合DNA, 主要用于标记坏死细胞。储存要求:避光。 | |||
T35270 |
YO-Pro 1
YO-Pro1,YO-Pro-1 |
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YO-Pro 1 是一种由苯并恶唑和喹啉环通过连接体连接而成的菁染料,在水中几乎没有荧光,但其荧光在插入双链DNA后大大增强,成为DNA浓度测定的基础,Ex/Em (结合DNA) = 491/509 nm。YO-Pro 1 可用于鉴定凋亡细胞。 | |||
T78446 |
Phenosafranine
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Phenosafranine是一种吩嗪染料,具有较高的三链RNA结合亲和力,相较于双链RNA。该染料通过嵌入机制与这两种RNA结合。Phenosafranine用途包括植物细胞染色,以及血红蛋白、多巴胺、血清素等的检测。 | |||
T69117 | Pinafide | ||
Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD⁺-dependent DNA ligase A at concentrations ... |