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Cat. No. Product Name Target Signaling Pathways
T1092 Zolmitriptan

佐米曲普坦,311C90,BW-311C90

5-HT Receptor GPCR/G Protein; Neuroscience
Zolmitriptan (311C90) 是一种5-HT1B/1D 受体部分激动剂,可用于偏头痛的研究,对 5-HT1B、5-HT1D、5-HT1F 受体的Ki 分别为 5.01、0.63 和 63.09 nM。
T17197 UCL 2077

UCL 2077 是癫痫相关 KCNQ 通道的亚型选择性阻滞剂,也是一种选择性慢后超极化通道阻滞剂,在培养的海马神经元中 IC50 为 500 nM,对 Ca2+ 通道、动作电位、输入电阻的影响小 ,以及超极化后的介质。
T71349 GRC-6211

GRC-6211 is an oral specific TRPV1 antagonist which decreases bladder overactivity and noxious bladder input in cystitis animal models.
T33699 NLCQ-1 HCl

NLCQ1,NLCQ-1, NLCQ 1,NSC 709257

NLCQ-1 is a novel weak DNA-intercalative bioreductive compound. NLCQ-1 exhibited a C50 of 44 microM. NLCQ-1 demonstrated significant hypoxic selectivity in several rodent (V79, EMT6, SCCVII) or human (A549, OVCAR-3) tumor cell lines. Its potency as a hypo
T37391 PSEM 308 hydrochloride

PSAM (pharmacologically selective actuator module) agonist. Activates PSAML141F-GlyR chimeric ion channels. Inhibits activity of neurons expressing PSAML141F-GlyR in vivo and activates locus coeruleus noradrenergic neurons expressing PSAML141F,Y115F-5-HT3 ion channels. Recommended concentration for use in mice is 5 mg/kg or lower. Plasmid vectors for the transfection of cells with PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 are available from Addgene. Lovett-Barron et al (2012) Regulation of neu...

化合物

Zolmitriptan
Cat.No: T1092
Synonym: 佐米曲普坦,311C90,BW-311C90
Target: 5-HT Receptor
UCL 2077
Cat.No: T17197
Synonym:
Target:
GRC-6211
Cat.No: T71349
Synonym:
Target:
NLCQ-1 HCl
Cat.No: T33699
Synonym: NLCQ1,NLCQ-1, NLCQ 1,NSC 709257
Target:
PSEM 308 hydrochloride
Cat.No: T37391
Synonym:
Target:
TargetMol Loading
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