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Cat. No. | Product Name | Target | Signaling Pathways |
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TP1542 |
26Rfa, Hypothalamic Peptide, human
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This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area. | |||
TP1648L |
[Gln8]-C517 (LH-RH), chicken acetate
[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) |
Others | Others |
[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) 是一种鸟类下丘脑肽,可刺激垂体前叶释放促性腺激素,从而调节生殖功能。 | |||
T9857 |
Vasopressin
antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) |
Endogenous Metabolite | Metabolism |
Vasopressin (argipressin) 是一种由下丘脑神经元合成的环状九肽,是肽原激素合成中的一种激素。Vasopressin 参与下丘脑-垂体-肾上腺轴调节过程,增加无溶质水从肾小管的滤液中重新吸收回循环中的量,收缩小动脉提高压强,增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 在神经传导过程中可作为神经递质,与特定的 G 蛋白偶联受体结合发挥作用。 | |||
TP1648 |
[Gln8]-C517 (LH-RH), chicken
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[Gln8] Luteinizing hormone releasing hormone ([Gln8] LH-RH), Avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions. | |||
T83148 |
Alarin (human)
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Alarin (human) 属于下丘脑甘丙肽家族,包含 GALP 前体肽的信号序列和成熟 GALP 前 5 个氨基酸。 | |||
T76290 |
Exendin-4 (3-39)
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Exendin-4 (3-39) 是一种肽。Exendin-4 (3-39) 是 Exendin-4 的截断形式,缺少前两个氨基酸。Exendin-4 是一种有效的 GLP-1r 激动剂。Exendin-4 (3-39) 和 Exendin-4 可用于糖尿病和下丘脑-垂体-肾上腺 (HPA) 轴的研究。 | |||
TP1247 |
ACTH (1-13)
Adrenocorticotropic Hormone (1-13),ACTH 1-13 |
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ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an impor | |||
T75898 |
CART(62-76)(human,rat) TFA
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CART(62-76)(human,rat) TFA 是一种类似神经递质的神经肽,由CART肽的62至76残基组成。该化合物能够调控纹状体去甲肾上腺素能、皮质纹状体及下丘脑在5-羟色胺能(5-HT)系统中的活性。 | |||
T69383 |
NBI-42902
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NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). Tritiated NBI-42902 binds with high affinity (K(d) = 0.19 nm) to a single class of binding sites and can be displaced by a range of peptide and nonpeptide GnRH receptor ligands. In vitro experiments demonstrate that NBI-42902 is a potent functional, competitive antagonist of GnRH stimulated IP accumulation, Ca(2+) flux, and ERK1/2 activation. It did not stimulate histamine release from rat... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T5145 |
Oxytocin acetate
Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。 |