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Cat. No. Product Name Target Signaling Pathways
T9231 Mbx2329

Antiviral Immunology/Inflammation
MBX2329 是一种流感病毒抑制剂,能特异性地抑制血凝素介导的病毒进入,HIV/HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。
T22838 hemagglutinin (332-340) [Influenza A virus]

Others Others
Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w
TP2232 hemagglutinin precursor (114-122) amide [Influenza A virus]

Others Others
Partial antigenic glycoprotein
TP1735L Influenza HA 126-138 acetate

Influenza HA 126-138 acetate(207349-63-1 free base)

Others Others
Influenza HA 126-138 acetate 是一种流感病毒血凝素 (HA) 肽乙酸盐,包含氨基酸 126-138。 它诱导胸腺和外周 T 细胞凋亡。
T8793 CBS1117

Influenza Virus Microbiology/Virology
CBS1117 是一种病毒进入抑制剂,对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。
T26873 BMY-27709

BMY 27709,BMY27709

Influenza Virus Microbiology/Virology
BMY-27709 是一种流感病毒生长抑制剂,对 A/WSN/33 病毒生长的 IC50 值为 3-8 μM,对流感病毒的部分亚型也展现出抑制活性。BMY-27709 对 H1 和 H2 病毒感染的早期起作用,通过抑制血凝素蛋白展现其抗病毒活性。然而,BMY-27709 对 H3 亚型病毒以及 B 型/Lee/40 流感病毒没有作用。
T27610 Ingavirin

Ingavirin, a novel inhibitor of the influenza virus reproduction, inhubits the formation of the virus specific hemagglutinin.
T62216 Influenza virus-IN-5

Influenza virus-IN-5 (Compound 5f) 是一种流感病毒血球凝集素 (hemagglutinin (HA)) 抑制剂,能够作用于 A/H3N2 病毒 (EC50: 1 nM)。
T15625 JNJ4796

Others Others
JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
T37466 CAY10766

CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus.
T38719 Influenza HA (110-119)

Influenza HA (110-119) refers to a specific fragment (110-119) derived from the hemagglutinin protein of the influenza virus. This fragment has the ability to induce the proliferation of Treg cells.
T74614 PROTAHemagglutinin Degrader-1

PROTACHemagglutinin Degrader-1 (Compound V3) 是一种有效的 PROTAC 流感病毒血凝素 (influenza hemagglutinin(HA)) 降解剂,降解中值浓度为 1.44 μM。PROTACHemagglutinin Degrader-1 具有广谱抗流感病毒活性。
TP1735 Influenza HA (126-138)

Influenza HA 126-138

Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) protein of the influenza virus. It consists of amino acids 126-138 and has the ability to induce apoptosis in both thymic and peripheral T-cells.
T68413 CBS1194

CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational change of hemagglutinin (HA). CBS1194 causes steric hinderance that prevents the rearrangement of the HA that would normally be induced by low-pH, by fitting into the pocket by the fusion peptide.
T77094 Navivumab

Navivumab (CT-P23)是针对甲型流感病毒(influenza A virus) HA血凝素的单克隆抗体。该药物通过结合HA2蛋白的茎融合结构域,能中和H1、H2、H5及H9型甲型流感病毒。
T79444 HA-IN-1

Influenza Virus Microbiology/Virology
HA-IN-1(compound 5g)是靶向血凝素(HA)胰蛋白酶切割位点的配体,表现出高亲和力。该化合物能够抑制HA介导的膜融合,并在体内有效降低肺部病毒滴度,展现其作为甲型流感病毒(IAV)抑制剂和抗流感药物的潜力。
T77021 Gedivumab

Gedivumab (MHAA4549A; RG7745),一种高特异性人源单克隆抗体,靶向甲型流感病毒 (IAV),通过与IAV血凝素蛋白的高度保守茎区结合,阻止其成熟并阻断核内体中的血凝素介导的膜融合,适用于IAV感染疾病研究。
T80279 Urumin

Influenza Virus Microbiology/Virology
Urumin 对人类甲型流感病毒显示出抗病毒活性,通过靶向 H1 血凝素的保守茎部位,能有效中和耐药 H1 流感病毒。它在抑制 PR8 流感病毒的生长中的半抑制浓度(IC50)为 3.8 μM,并能保护幼鼠免遭致命流感病毒感染。
T77009 Firivumab

Firivumab (CT-P22; CT120)是一种针对人类IgG1单克隆的抗甲型流感病毒血凝素(Anti-IAV HA)抗体。该抗体能有效中和多种亚型,包括H1N1、H5N1、H6N1、H6N2、H8N4、H8N8、H9N2和H12N7。研究发现,Firivumab在小鼠模型中对H1N1病毒展现出显著的保护效果。

化合物

Mbx2329
Cat.No: T9231
Synonym:
Target: Antiviral
hemagglutinin (332-340) [Influenza A virus]
Cat.No: T22838
Synonym:
Target: Others
hemagglutinin precursor (114-122) amide [Influenza A virus]
Cat.No: TP2232
Synonym:
Target: Others
Influenza HA 126-138 acetate
Cat.No: TP1735L
Synonym: Influenza HA 126-138 acetate(207349-63-1 free base)
Target: Others
CBS1117
Cat.No: T8793
Synonym:
Target: Influenza Virus
BMY-27709
Cat.No: T26873
Synonym: BMY 27709,BMY27709
Target: Influenza Virus
Ingavirin
Cat.No: T27610
Synonym:
Target:
Influenza virus-IN-5
Cat.No: T62216
Synonym:
Target:
JNJ4796
Cat.No: T15625
Synonym:
Target: Others
CAY10766
Cat.No: T37466
Synonym:
Target:
Influenza HA (110-119)
Cat.No: T38719
Synonym:
Target:
PROTAHemagglutinin Degrader-1
Cat.No: T74614
Synonym:
Target:
Influenza HA (126-138)
Cat.No: TP1735
Synonym: Influenza HA 126-138
Target:
CBS1194
Cat.No: T68413
Synonym:
Target:
Navivumab
Cat.No: T77094
Synonym:
Target:
HA-IN-1
Cat.No: T79444
Synonym:
Target: Influenza Virus
Gedivumab
Cat.No: T77021
Synonym:
Target:
Urumin
Cat.No: T80279
Synonym:
Target: Influenza Virus
Firivumab
Cat.No: T77009
Synonym:
Target:
TargetMol Loading
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