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11

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
TD0102 1,3-Diphenylisobenzofuran

DPBF

Others Others
1,3-Diphenylisobenzofuran (DPBF) 是一种荧光探针,对单线态氧(1O2) 的具有高特异性,可形成内过氧化物并分解成 1,2-dibenzoylbenzene,可用于活性氧生成的检测。
T70694 HA-29

HA-29 is an inhibitor of thromboxane A2 and prostaglandin endoperoxide receptors.
T24296 L 640035

L640035,L 640,035,L-640035,L640,035,L-640,035

L 640035 inhibits human platelet aggregation which is induced by arachidonic acid, collagen, and the prostaglandin-endoperoxide analog of U44069.
T32720 Levuglandin E2

Levuglandin E2 is a secoprostanoid from prostaglandin endoperoxide.
T22897 L-670,596

Others Others
L-670,596 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist.
T22896 L-655,240

Others Others
L-655,240 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist.
T28242 Ono 3708

Ono-3708,Ono3708

Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo.
T71035 KT2-962

KT2-962 is a TXA2/prostaglandin endoperoxide receptor antagonist.
T17189 U-46619

9,11-Methanoepoxy PGH2

Progesterone Receptor; PPAR DNA Damage/DNA Repair; Metabolism; Others
U-46619是一种有效的TXA2激动剂,是一种血栓素A2类似物(内过氧化物),有诱导肌球蛋白轻链9 (Myl9)基因缺失小鼠主动脉平滑肌(SM)收缩的功能。
T11813 Laflunimus

HR325

Others Others
Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. Laflunimus is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH).
T35991 ent-Prostaglandin E2

ent-Prostaglandin E2

Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), g...

化合物

1,3-Diphenylisobenzofuran
Cat.No: TD0102
Synonym: DPBF
Target: Others
HA-29
Cat.No: T70694
Synonym:
Target:
L 640035
Cat.No: T24296
Synonym: L640035,L 640,035,L-640035,L640,035,L-640,035
Target:
Levuglandin E2
Cat.No: T32720
Synonym:
Target:
L-670,596
Cat.No: T22897
Synonym:
Target: Others
L-655,240
Cat.No: T22896
Synonym:
Target: Others
Ono 3708
Cat.No: T28242
Synonym: Ono-3708,Ono3708
Target:
KT2-962
Cat.No: T71035
Synonym:
Target:
U-46619
Cat.No: T17189
Synonym: 9,11-Methanoepoxy PGH2
Target: Progesterone Receptor, PPAR
Laflunimus
Cat.No: T11813
Synonym: HR325
Target: Others
ent-Prostaglandin E2
Cat.No: T35991
Synonym: ent-Prostaglandin E2
Target:
Cat. No. Product Name Target Signaling Pathways
T73066 Thielavin B

Thielavin B为Thielavin terricola产生的前列腺素生物合成抑制剂。该化合物能有效抑制内过氧物酶介导的前列腺素E2合成,并在静脉注射后显著降低大鼠因角叉菜胶引发的水肿。

天然产物

Thielavin B
Cat.No: T73066
Synonym:
Target:
TargetMol Loading
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