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Cat. No. | Product Name | Target | Signaling Pathways |
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TD0102 |
1,3-Diphenylisobenzofuran
DPBF |
Others | Others |
1,3-Diphenylisobenzofuran (DPBF) 是一种荧光探针,对单线态氧(1O2) 的具有高特异性,可形成内过氧化物并分解成 1,2-dibenzoylbenzene,可用于活性氧生成的检测。 | |||
T70694 |
HA-29
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HA-29 is an inhibitor of thromboxane A2 and prostaglandin endoperoxide receptors. | |||
T24296 |
L 640035
L640035,L 640,035,L-640035,L640,035,L-640,035 |
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L 640035 inhibits human platelet aggregation which is induced by arachidonic acid, collagen, and the prostaglandin-endoperoxide analog of U44069. | |||
T32720 |
Levuglandin E2
|
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Levuglandin E2 is a secoprostanoid from prostaglandin endoperoxide. | |||
T22897 |
L-670,596
|
Others | Others |
L-670,596 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist. | |||
T22896 |
L-655,240
|
Others | Others |
L-655,240 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist. | |||
T28242 |
Ono 3708
Ono-3708,Ono3708 |
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Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo. | |||
T71035 |
KT2-962
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KT2-962 is a TXA2/prostaglandin endoperoxide receptor antagonist. | |||
T17189 |
U-46619
9,11-Methanoepoxy PGH2 |
Progesterone Receptor; PPAR | DNA Damage/DNA Repair; Metabolism; Others |
U-46619是一种有效的TXA2激动剂,是一种血栓素A2类似物(内过氧化物),有诱导肌球蛋白轻链9 (Myl9)基因缺失小鼠主动脉平滑肌(SM)收缩的功能。 | |||
T11813 |
Laflunimus
HR325 |
Others | Others |
Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. Laflunimus is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). | |||
T35991 |
ent-Prostaglandin E2
ent-Prostaglandin E2 |
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Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), g... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T73066 |
Thielavin B
|
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Thielavin B为Thielavin terricola产生的前列腺素生物合成抑制剂。该化合物能有效抑制内过氧物酶介导的前列腺素E2合成,并在静脉注射后显著降低大鼠因角叉菜胶引发的水肿。 |