4
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4504 |
Triclocarban
Solubacter,Cutisan,Procutene,3,4,4′-Trichlorocarbanilide,三氯卡班 |
Antibacterial | Microbiology/Virology |
Triclocarban (Cutisan) 是一种抗菌剂,用于个人清洁产品。它有潜在干扰内分泌的作用,具有调节雄激素和雌激素活性以及其他激素介导的生物过程的能力。 | |||
T41244 |
Triticonazole
|
Antifungal | Microbiology/Virology |
Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。 | |||
T20274 |
Dibenzyl phthalate
AI300364,AI3-00364 |
||
Dibenzyl phthalate is an endocrine-disrupting chemical. It also interferes with different cell signaling pathways involved in weight and glucose homeostasis. | |||
T39306 |
7-Oxodehydroabietic acid
|
||
7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5623 |
Bisphenol A
|
Others; Endogenous Metabolite | Metabolism; Others |
Bisphenol A 是酚类内源性代谢合成物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
T64353 |
4-tert-Octylphenol
|
Endogenous Metabolite | Metabolism |
4-tert-Octylphenol 是一种干扰内分泌的化学物质及雌激素药物,能诱导子代小鼠脑神经元祖细胞的凋亡,并通过减少溴脱氧尿苷(BrdU)、有丝分裂标志物Ki67以及磷酸组蛋白H3(p-Histone-H3)的表达,导致神经元祖细胞的增殖减少。这种物质不仅会干扰小鼠的大脑发育,还会影响其行为。 |