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Search Results for " echinocandin "

13

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9264	ECBN HCL 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)	Others	Others
	ECBN HCL (A-30912A nucleus hydrochloride) 是一种 Echinocandin B 脱酰酶催化反应的产物。
T12732	Rezafungin 棘白菌素,SP-3025,CD101,Biafungin	Others; Antifungal	Microbiology/Virology; Others
	Rezafungin (SP-3025) 是一种长效的广谱棘皮菌素，对念珠菌、曲霉和肺孢子菌具有强效抗真菌活性。
T24866	Tetrahydroechinocandin B L 687,901,L-687901,L-687,901,L687,901,L 687901
	Tetrahydroechinocandin B is a cyclic hexapeptide containing a fatty acyl side chain. It also inhibits 1,3-beta-D-glucan synthesis.
T1799	Caspofungin Acetate 醋酸卡泊芬净,L 743873,Cancidas,MK 0991,L 743872	Antibiotic; Antifungal	Microbiology/Virology
	Caspofungin Acetate (MK 0991) 是一种抗真菌药，能够非竞争性地抑制 1,3-β-D 葡聚糖合酶的合成。
T6088	Anidulafungin LY303366,Eraxis,Ecalta,阿尼芬净	Others; Antibiotic; Antifungal	Microbiology/Virology; Others
	Anidulafungin (Ecalta) 是一种半合成的新棘球白素，具有抗真菌作用。
T1794	Micafungin sodium Mycamine Sodium,FK 463,FK463 Sodium,米卡芬净钠	Antibiotic; Antifungal	Microbiology/Virology
	Micafungin sodium (FK 463) 是抗真菌剂，抑制1, 3-beta-D-glucan 的合成。
T25308	Deoxymulundocandin
	Deoxymulundocandin is an echinocandin type antifungal antibiotic from Aspergillus sydowii.
T70350	Caspofungin
	Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.
T12732L	Rezafungin acetate Biafungin acetate,SP-3025 acetate,CD101 acetate	Others	Others
	Rezafungin acetate is an advanced echinocandin compound that exhibits broad-spectrum antifungal activity against Candida spp, Aspergillus spp, and Pneumocystis spp. This long-lasting next-generation medication showcases potent efficacy in combating fungal infections.
T36024	FR179642 (hydrate) FR179642 (hydrate)
	FR179642 is the cyclic peptide nucleus of the lipopeptide antifungal FR901379 and an intermediate in the synthesis of the echinocandin antifungal FK463 .1,2 1.Tomishima, M., Ohki, H., Yamada, A., et al.FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activityJ. Antibiot. (Tokyo)52(7)674-676(1999) 2.Ueda, S., Shibata, T., Ito, K., et al.Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907J. Antibiot. (Tokyo)64(2)169-175(2011)
T75712	Aminocandin
	Aminocandin (HMR 3270) 是一种水溶性的棘白菌素类抗真菌剂 (antifungal)，对 Aspergillus 和 Candidaspp. 具有良好的活性。
T68780	Puupehenone
	Puupehenone is a natural heat shock protein 90 (Hsp90) inhibitor, potentiating the echinocandin drug caspofungin in caspofungin-resistant fungal pathogens, blocking the induction of caspofungin-responding genes required for the adaptation to cell wall stress through the cell wall integrity (CWI) pathway.
T35700	FR901379
	FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection. \|1. Fujie, A., Iwamoto, T., Sato, B., et al. FR131535, a novel water-soluble echinocandin-like lipopeptide: Synthesis and bi...

化合物

Cat.No: T9264

Synonym: 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)

Target: Others

Cat.No: T12732

Synonym: 棘白菌素,SP-3025,CD101,Biafungin

Target: Others, Antifungal

Tetrahydroechinocandin B

Cat.No: T24866

Synonym: L 687,901,L-687901,L-687,901,L687,901,L 687901

Caspofungin Acetate

Cat.No: T1799

Synonym: 醋酸卡泊芬净,L 743873,Cancidas,MK 0991,L 743872

Target: Antibiotic, Antifungal

Cat.No: T6088

Synonym: LY303366,Eraxis,Ecalta,阿尼芬净

Target: Others, Antibiotic, Antifungal

Micafungin sodium

Cat.No: T1794

Synonym: Mycamine Sodium,FK 463,FK463 Sodium,米卡芬净钠

Target: Antibiotic, Antifungal

Deoxymulundocandin

Cat.No: T25308

Cat.No: T70350

Rezafungin acetate

Cat.No: T12732L

Synonym: Biafungin acetate,SP-3025 acetate,CD101 acetate

Target: Others

FR179642 (hydrate)

Cat.No: T36024

Synonym: FR179642 (hydrate)

Cat.No: T75712

Cat.No: T68780

Cat.No: T35700

Cat. No.	Product Name	Target	Signaling Pathways
T27237	Echinocandin B A-30912A,NSC 287461,A 30912A,A30912A,A22082
	Echinocandin B is a cyclic hexapeptide echinocandin antibiotic from Aspergillus nidulans var. echinulatus . It attacks the cell wall of fungi by inhibiting beta-1,3-glucan synthesis.
T39148	FR179642 FR179642
	FR179642 is an essential intermediate compound utilized in the synthesis of Micafungin, an antifungal drug belonging to the echinocandin class. It serves as the cyclic peptide foundation for the structurally similar antifungal lipopeptide FR901379.

天然产物

Echinocandin B

Cat.No: T27237

Synonym: A-30912A,NSC 287461,A 30912A,A30912A,A22082

Cat.No: T39148

Synonym: FR179642

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