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Cat. No. | Product Name | Target | Signaling Pathways |
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T0382 |
Eprodisate disodium
NC-503,伊罗地塞二钠,伊罗地塞二钠盐 |
Others | Others |
Eprodisate disodium (NC-503) 是一种带负电荷的磺化类的原纤维形成抑制剂,是口服具有活力的 Eprodisate 二钠盐形式,可用于研究淀粉样蛋白A(AA) 淀粉样变性病。 | |||
T31527 | Disalicylalpropylenediimine | ||
Disalicylalpropylenediimine is a biochemical. | |||
T37851 |
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
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Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging... | |||
T39638 |
Eprodisate
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Eprodisate is a novel compound specifically developed to disrupt the interactions between amyloidogenic proteins and glycosaminoglycans, effectively impeding the polymerization of amyloid fibrils and their deposition in tissues. This compound shows potential for delaying the advancement of AA amyloidosis-related renal disease and could apply to various forms of amyloidosis. | |||
T24863 |
Tedisamil
Tedisamilum,Pulzium |
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Tedisamil is a blocker of K+ currents in cardiac tissues, exerts bradycardic effects. It is an antiarrhythmic drug with predominantly class III activity. It has shown clinical efficacy in angina pectoris. | |||
T70524 |
Tedisamil sesquifumarate
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Tedisamil sesquifumarate is an Antiarrhythmic Agent (K(sup +) Channel Blocker) | |||
T71874 |
ST056083
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ST056083 is an inhibitor of the c-di-AMP synthetase DNA integrity scanning protein (DisA) in vitro. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T83564 |
(2E,4E)-8-Hydroxy-2,7-dimethyl-decadien-(2,4)-disaeure-(1,10)-dioic acid
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'(2E,4E)-8-Hydroxy-2,7-dimethyl-decadien-(2,4)-disaeure-(1,10)-dioic acid',作为一种从木耳花中分离得到的天然产物,展现出抗氧化和抗炎的活性。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-02993 |
DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc)
disA,c-di-AMP synthase,DNA integrity scanning prote... |
Mycobacterium paratuberculosis | E. coli |
Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predict... |