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9

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T6710	Troxipide 曲昔派特,曲昔匹特,Aplace	Others	Others
	Troxipide (Aplace) 是非分泌型胃保护剂，是口服具有活力的胃炎和胃溃疡的防御因子的增强剂，具有抗溃疡、抗炎和粘液分泌作用。
TP1573L	CLIP 86-100 acetate(648881-58-7 free base)	Others	Others
	CLIP 86-100 acetate(648881-58-7 free base) 这是称为 CLIP 的 II 类相关不变链肽的氨基酸 86 至 100 片段。主要组织相容性复合物 II 类分子显示外源蛋白的肽片段，以触发免疫系统的防御反应。在将外源肽插入结合槽之前，去除一个占位肽 CLIP。这是通过分子 DM 实现的，它被证明可以增加 CLIP 肽与 II 类的解离速率。
T69160	DMNT
	DMNT is a natural homoterpene, being sufficient for a volatile-mediated systemic induction of defensive Sporamin protease inhibitor activity in neighboring sweet potato plants.
T39306	7-Oxodehydroabietic acid
	7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system.
T33799	Onchidal
	Onchidal is a major lipid-soluble component of the defensive secretion of the mollusk Onchidella binneyi and is responsible for the chemical protection of Onchidella.
TP2067	Cortagine
	Potent and selective corticotrophin releasing factor receptor 1 (CRF1) agonist (EC50 = 0.18 nM for rat CRF1). Displays anxiolytic and antidepressant activity in vivo. Microinfusion into mouse prefrontal cortex reduces defensive behavior in vivo.
TP1573	CLIP (86-100) CLIP 86-100
	CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. CLIP (86-100) is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class...
T26855	BMS-665053 BMS665053
	BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM). In addi
T37295	Ganglioside GM1 Asialo Mixture
	Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na...

化合物

Cat.No: T6710

Synonym: 曲昔派特,曲昔匹特,Aplace

Target: Others

CLIP 86-100 acetate(648881-58-7 free base)

Cat.No: TP1573L

Target: Others

Cat.No: T69160

7-Oxodehydroabietic acid

Cat.No: T39306

Cat.No: T33799

Cat.No: TP2067

Cat.No: TP1573

Synonym: CLIP 86-100

Cat.No: T26855

Synonym: BMS665053

Ganglioside GM1 Asialo Mixture

Cat.No: T37295

Cat. No.	Product Name	Target	Signaling Pathways
T5747	ISOBERGAPTEN	Others	Others
	Isobergapten 是一种化感抑制剂，分离自Hevacleum laciniatum 种子。

天然产物

Cat.No: T5747

Target: Others

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