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15

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8123	Diazolidinyl urea Germall II,重氮烷基脲	Others; Antibacterial	Microbiology/Virology; Others
	Diazolidinyl urea (Germall II) 是一种甲醛释放防腐剂，用于化妆品和个人护理产品。它对大多数污染微生物，特别是假单胞菌都有效。
T22447	Tri-Salicylic Acid 三水杨酸	Others	Others
	Tri-Salicylic acid 是一种和水杨酸具有相似性质的化合物。它对肥胖、炎症及心血管疾病具有潜在的研究价值。
T20381	Cetyl glycol NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525	Others	Others
	Cetyl glycol (NSC-71525) 有利于金属有机前体的分解、中间体 Co(2+)Fe(3+)-油酸配合物的形成以及纳米颗粒在较低温度下的成核。 Cetyl glycol 是一种可用于化妆品的还原剂。
T1366	3-Pyridylacetic acid hydrochloride	DPP-4	Proteases/Proteasome
	3-Pyridylacetic acid hydrochloride （3-PAA-HCl）尼克酸的高同系物，是尼古丁（和其它烟草生物碱）的分解产物，还可与胺、醇和羧酸等反应，也可在反应中作为酸催化剂。
T20608	3-Benzoylpyridine 3 Benzoylpyridine,Phenyl 3-pyridyl ketone,3-苯甲酰基吡啶,Pyridine, 3-benzoyl-	Others	Others
	3-Benzoylpyridine (Phenyl 3-pyridyl ketone) 是人体解毒剂 HGG-12的分解产物。
T27314	Fe-TMPyP
	Fe-TMPyP binds to the prion protein PrP and inhibits misfolding. Fe-TMPyP is also a peroxynitrite decomposition catalyst.
T36352L	Suc-Leu-Tyr-AMC Acetate Suc-Leu-Tyr-AMC Acetate(94367-20-1 Free base）	Others	Others
	Suc-Leu-Tyr-AMC Acetate 在高浓度时抑制酪蛋白分解。
T35966	Mn(III)TMPyP
	Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, re...
T39324	2,3-Dimethyl-2,3-diphenylbutane
	2,3-Dimethyl-2,3-diphenylbutane is a byproduct of the decomposition of Dicumylperoxide (DCP). It serves as an initiator for Diallyl orthophthalate (DAOP), a reactive plasticizer that is used to enhance the processing of polyphenylene oxide (PPO) in manufacturing.
T76097	Aldolase
	Aldolase 是一种糖酵解酶，也是 vATP 酶复合物的组成部分。Aldolase 可使 1，6-二磷酸果糖分解成二羟基丙酮和 3-磷酸甘油醛。
T35996	FeTPPS
	Peroxynitrite is a highly reactive nitrogen species formed from the reaction of nitric oxide (NO) and superoxide.[1] FeTPPS is a ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomerization to produce nitrate both in vitro and in vivo. The conversion of this reactive nitrogen species to nitrate results in cytoprotection (EC50 = 5 &#181M). [2][3] FeTPPS does not complex with NO and does not alter superoxide directly. It is commonly used to elucidate the roles...
T36026	DEPMPO 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
	DEPMPO is a phosphorylated derivative of the widely used DMPO spin trap. It has been reported to produce spin adducts with increased stability particularly for the adduct of superoxide. [1] [2] [3] DEPMPO displays a detectable spin adduct signal at a concentration as low as 1 mM, as compared to 5 mM for DMPO.[3] A significant advantage of using DEPMPO in trapping superoxide radical is that the decomposition of DEPMPO/O2 - does not produce the OH adduct, which can be a drawback when using DMPO....
T37276	2,5-Deoxyfructosazine (hydrochloride)
	2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL...
T36508	trans-4,5-epoxy-2(E)-Decenal trans-4,5-epoxy-2(E)-Decenal,3-(3-pentyloxiranyl)-2E-propenal
	Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of d...
T36175	AAPH
	AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces molecular nitrogen and 2 carbon radicals. The carbon radicals may combine to produce stable products or react with molecular oxygen to give peroxyl radicals. The half-life of AAPH is about 175 hours (37°C at neutral pH), making the rate of free radical generation essentially con...

化合物

Diazolidinyl urea

Cat.No: T8123

Synonym: Germall II,重氮烷基脲

Target: Others, Antibacterial

Tri-Salicylic Acid

Cat.No: T22447

Synonym: 三水杨酸

Target: Others

Cat.No: T20381

Synonym: NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525

Target: Others

3-Pyridylacetic acid hydrochloride

Cat.No: T1366

Target: DPP-4

3-Benzoylpyridine

Cat.No: T20608

Synonym: 3 Benzoylpyridine,Phenyl 3-pyridyl ketone,3-苯甲酰基吡啶,Pyridine, 3-benzoyl-

Target: Others

Cat.No: T27314

Suc-Leu-Tyr-AMC Acetate

Cat.No: T36352L

Synonym: Suc-Leu-Tyr-AMC Acetate(94367-20-1 Free base）

Target: Others

Cat.No: T35966

2,3-Dimethyl-2,3-diphenylbutane

Cat.No: T39324

Cat.No: T76097

Cat.No: T35996

Cat.No: T36026

Synonym: 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide

2,5-Deoxyfructosazine (hydrochloride)

Cat.No: T37276

trans-4,5-epoxy-2(E)-Decenal

Cat.No: T36508

Synonym: trans-4,5-epoxy-2(E)-Decenal,3-(3-pentyloxiranyl)-2E-propenal

Cat.No: T36175

Cat. No.	Product Name	Target	Signaling Pathways
T2934	Bilirubin 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin	Endogenous Metabolite	Metabolism
	Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物，是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。
T2O2798	D-(+)-Trehalose Ergot Sugar,D-Trehalose,Mycose,D-(+)-Trehalose Anhydrous,D-海藻糖,Trehalose	Others; Endogenous Metabolite	Metabolism; Others
	D-(+)-Trehalose (Mycose) 来源于自Saccharomyces cerevisiae，常用作食品成分和药物赋形剂。
T40712	Diethyl fumarate	Others	Others
	Diethyl fumarate 是农药马拉硫磷的分解产物。 Diethyl fumarate 会在皮肤上引起非免疫性接触性荨麻疹。
T4827	Trimethylammonium chloride 三甲胺盐酸盐,Trimethylamine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Trimethylammonium chloride (Trimethylamine hydrochloride) 是动植物分解的产物。它是造成鱼腥味的主要物质，通常与脏鱼、细菌性阴道感染和口臭有关。它也与服用大剂量胆碱有关。三甲胺尿是一种遗传性疾病，身体无法从食物中代谢三甲胺。食用富含胆碱的食物后，患者的汗液、尿液和呼吸中会出现特有的鱼腥味。三甲胺尿症是一种常染色体隐性遗传病，涉及三甲胺氧化酶缺乏症。三甲氨基尿症在罗德岛红鸡中也有发现，这种鸡产的蛋有腥味。尿液中的 Trimethylammonium chloride 是食用豆类的生物标志物。

天然产物

Cat.No: T2934

Synonym: 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin

Target: Endogenous Metabolite

D-(+)-Trehalose

Cat.No: T2O2798

Synonym: Ergot Sugar,D-Trehalose,Mycose,D-(+)-Trehalose Anhydrous,D-海藻糖,Trehalose

Target: Others, Endogenous Metabolite

Diethyl fumarate

Cat.No: T40712

Target: Others

Trimethylammonium chloride

Cat.No: T4827

Synonym: 三甲胺盐酸盐,Trimethylamine hydrochloride

Target: Others, Endogenous Metabolite

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