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Cat. No. Product Name Target Signaling Pathways
T11291 FKBP12 PROTAC dTAG-13

dTAG-13

Epigenetic Reader Domain Chromatin/Epigenetic
FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN. FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader.
T36252 dTAG-13-NEG

Negative control for dTAG-13.
T40031 Thalidomide-O-C6-NH2 hydrochloride

4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐

E3 Ligase Ligand-Linker Conjugate PROTAC
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) 是一种合成的E3 连接酶配体 -linker 偶联物,用于 PROTAC dTAG-13 的合成。其中 dTAG-13 是一种 FKBP12F36V 和 BET 的降解剂。
T18824 Thalidomide-O-C6-NH2 TFA

Others Others
Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
T18825 Thalidomide-O-C6-NH2

Others Others
Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].

化合物

FKBP12 PROTAC dTAG-13
Cat.No: T11291
Synonym: dTAG-13
Target: Epigenetic Reader Domain
dTAG-13-NEG
Cat.No: T36252
Synonym:
Target:
Thalidomide-O-C6-NH2 hydrochloride
Cat.No: T40031
Synonym: 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐
Target: E3 Ligase Ligand-Linker Conjugate
Thalidomide-O-C6-NH2 TFA
Cat.No: T18824
Synonym:
Target: Others
Thalidomide-O-C6-NH2
Cat.No: T18825
Synonym:
Target: Others
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