首页工具

登录

搜索结果

Search Results for " ciap1 ligand 1 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T17870	cIAP1 ligand 1 E3 ligase Ligand 12	Others	Others
	cIAP1 ligand 1 (E3 ligase Ligand 12) 是基于 LCL161 衍生物的细胞凋亡蛋白配体，可募集 IAP 泛素连接酶以降解靶蛋白，可用于和雄激素受体配体偶联开发蛋白降解剂，可用于研究前列腺癌。
T39609	cIAP1 Ligand-Linker Conjugates 16 cIAP1 Ligand-Linker Conjugates 16
	cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
T17895	cIAP1 Ligand-Linker Conjugates 1 E3 ligase Ligand-Linker Conjugates 41	Others	Others
	cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1].
T17899	cIAP1 Ligand-Linker Conjugates 9 E3 ligase Ligand-Linker Conjugates 45	Others	Others
	cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1].
T17869	cIAP1 ligand 2 E3 ligase Ligand 11	Others	Others
	cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
T17889	cIAP1 Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 36	Others	Others
	cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1].
T17896	cIAP1 Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 42	Others	Others
	cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potential to be utilized in the development of SNIPERs[1].
T17885	cIAP1 Ligand-Linker Conjugates 11 E3 ligase Ligand-Linker Conjugates 33	Others	Others
	cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.
T17891	cIAP1 Ligand-Linker Conjugates 2 E3 ligase Ligand-Linker Conjugates 37	Others	Others
	cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1].
T17893	cIAP1 Ligand-Linker Conjugates 5 E3 ligase Ligand-Linker Conjugates 39	Others	Others
	cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for the development of SNIPERs[1].
T17888	cIAP1 Ligand-Linker Conjugates 6 hydrochloride E3 ligase Ligand-Linker Conjugates 35 hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
T17894	cIAP1 Ligand-Linker Conjugates 3 E3 ligase Ligand-Linker Conjugates 40	Others	Others
	cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find utility in the design of SNIPERs, short for Specific and Non-genetic IAP-dependent Protein Erasers [1].
T17898	cIAP1 Ligand-Linker Conjugates 7 E3 ligase Ligand-Linker Conjugates 44	Others	Others
	cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1].
T17892	cIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-Linker Conjugates 38	Others	Others
	cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creating SNIPERs[1].
T17887	cIAP1 Ligand-Linker Conjugates 15 E3 ligase Ligand-Linker Conjugates 34	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
T17897	cIAP1 Ligand-Linker Conjugates 13 E3 ligase Ligand-Linker Conjugates 43	Others	Others
	cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
T17900	cIAP1 Ligand-Linker Conjugates 8 E3 ligase Ligand-Linker Conjugates 46	Others	Others
	cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].
T17901	cIAP1 Ligand-Linker Conjugates 10 E3 ligase Ligand-Linker Conjugates 47	Others	Others
	cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10.
T17886	cIAP1 Ligand-Linker Conjugates 15 hydrochloride E3 ligase Ligand-Linker Conjugates 34 hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
T17884	cIAP1 Ligand-Linker Conjugates 11 Hydrochloride E3 ligase Ligand-Linker Conjugates 33 Hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
T17890	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)	Others	Others
	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
T18635	PROTAC RAR Degrader-1	Others; PROTACs	Others; PROTAC
	PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
T17706	BzNH-BS	Others	Others
	BzNH-BS is a chemical compound comprising two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide. The ligands are interconnected through linkers. MeBS functions as a ligand for cIAP1, a ubiquitin ligase involved in cellular inhibition of apoptosis processes [1].
T14288	Androstanolone acetate	Others	Others
	Androstanolone acetate is a compound that functions as an androgen ligand, specifically targeting the androgen receptor (AR). It binds to the cIAP1 ligand Bestatin through a linker, resulting in the formation of PROTACs[1].
T18650	Ch55-O-C3-NH2 RAR ligand 1	Others	Others
	Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts with cIAP1 ligand Bestatin to form SNIPER[1].
T17940	Estrone-N-O-C1-amido ERα ligand 1	Others	Others
	Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-O-C1-amido (ERα ligand 1) forms a complex with the cIAP1 ligand Bestatin, leading to the creation of SNIPER[1].
T18596	PROTAC AR Degrader-4	Others	Others
	PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
T17545	Biotin-BS	Others	Others
	Biotin-BS is a chemical compound composed of two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and biotin. These ligands are interconnected through linkers. MeBS serves as a ligand specifically for the cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase[1].
T17733	ATRA-hydroxyimino CRABP-II ligand 1	Others	Others
	ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
T18605	PROTAC ERα Degrader-2	Others; PROTACs	Others; PROTAC
	PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
T18696	SNIPER(ER)-110	Others	Others
	SNIPER(ER)-110 consists of a cIAP1 ligand and an estrogen ligand, connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively[1].
T18690	SNIPER(ABL)-039	Others	Others
	SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, cIAP1, cIAP2, XIAP, respectively[1].
T73726	PROTAC AR Degrader-4 TFA	PROTACs	PROTAC
	PROTACAR Degrader-4 包含IAP 配体结合基团，linker 和雄激素受体 (AR) 配体结合基团。基于cIAP1的降解剂也被称为SNIPER。

化合物

cIAP1 ligand 1

Cat.No: T17870

Synonym: E3 ligase Ligand 12

Target: Others

cIAP1 Ligand-Linker Conjugates 16

Cat.No: T39609

Synonym: cIAP1 Ligand-Linker Conjugates 16

cIAP1 Ligand-Linker Conjugates 1

Cat.No: T17895

Synonym: E3 ligase Ligand-Linker Conjugates 41

Target: Others

cIAP1 Ligand-Linker Conjugates 9

Cat.No: T17899

Synonym: E3 ligase Ligand-Linker Conjugates 45

Target: Others

cIAP1 ligand 2

Cat.No: T17869

Synonym: E3 ligase Ligand 11

Target: Others

cIAP1 Ligand-Linker Conjugates 14

Cat.No: T17889

Synonym: E3 ligase Ligand-Linker Conjugates 36

Target: Others

cIAP1 Ligand-Linker Conjugates 4

Cat.No: T17896

Synonym: E3 ligase Ligand-Linker Conjugates 42

Target: Others

cIAP1 Ligand-Linker Conjugates 11

Cat.No: T17885

Synonym: E3 ligase Ligand-Linker Conjugates 33

Target: Others

cIAP1 Ligand-Linker Conjugates 2

Cat.No: T17891

Synonym: E3 ligase Ligand-Linker Conjugates 37

Target: Others

cIAP1 Ligand-Linker Conjugates 5

Cat.No: T17893

Synonym: E3 ligase Ligand-Linker Conjugates 39

Target: Others

cIAP1 Ligand-Linker Conjugates 6 hydrochloride

Cat.No: T17888

Synonym: E3 ligase Ligand-Linker Conjugates 35 hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 3

Cat.No: T17894

Synonym: E3 ligase Ligand-Linker Conjugates 40

Target: Others

cIAP1 Ligand-Linker Conjugates 7

Cat.No: T17898

Synonym: E3 ligase Ligand-Linker Conjugates 44

Target: Others

cIAP1 Ligand-Linker Conjugates 12

Cat.No: T17892

Synonym: E3 ligase Ligand-Linker Conjugates 38

Target: Others

cIAP1 Ligand-Linker Conjugates 15

Cat.No: T17887

Synonym: E3 ligase Ligand-Linker Conjugates 34

Target: Others

cIAP1 Ligand-Linker Conjugates 13

Cat.No: T17897

Synonym: E3 ligase Ligand-Linker Conjugates 43

Target: Others

cIAP1 Ligand-Linker Conjugates 8

Cat.No: T17900

Synonym: E3 ligase Ligand-Linker Conjugates 46

Target: Others

cIAP1 Ligand-Linker Conjugates 10

Cat.No: T17901

Synonym: E3 ligase Ligand-Linker Conjugates 47

Target: Others

cIAP1 Ligand-Linker Conjugates 15 hydrochloride

Cat.No: T17886

Synonym: E3 ligase Ligand-Linker Conjugates 34 hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 11 Hydrochloride

Cat.No: T17884

Synonym: E3 ligase Ligand-Linker Conjugates 33 Hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 2 Hydrochloride

Cat.No: T17890

Synonym: E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)

Target: Others

PROTAC RAR Degrader-1

Cat.No: T18635

Target: Others, PROTACs

Cat.No: T17706

Target: Others

Androstanolone acetate

Cat.No: T14288

Target: Others

Cat.No: T18650

Synonym: RAR ligand 1

Target: Others

Estrone-N-O-C1-amido

Cat.No: T17940

Synonym: ERα ligand 1

Target: Others

PROTAC AR Degrader-4

Cat.No: T18596

Target: Others

Cat.No: T17545

Target: Others

ATRA-hydroxyimino

Cat.No: T17733

Synonym: CRABP-II ligand 1

Target: Others

PROTAC ERα Degrader-2

Cat.No: T18605

Target: Others, PROTACs

Cat.No: T18696

Target: Others

SNIPER(ABL)-039

Cat.No: T18690

Target: Others

PROTAC AR Degrader-4 TFA

Cat.No: T73726

Target: PROTACs

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼