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41

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22373	ADA ADA buffer,N-(2-Acetamido)-2-Iminodiacetic acid,N-(2-乙酰氨基)-亚氨基二醋酸	Others	Others
	ADA (N-(2-Acetamido)-2-Iminodiacetic acid) 是一种生物缓冲液，可用作螯合剂。
T17043	TES	Others	Others
	TES 可用于制备 pH 范围为 6.8-8.2 的缓冲溶液，其 pKa 值为 7.550。
T22606	BIS-TRIS	Others	Others
	Bis-Tris 是常用的缓冲液之一。
T64722	IP Lysis Buffer
	IP Lysis Buffer 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64722。
T64666	10× Tris-Glycine Transfer Buffer
	10× Tris-Glycine Transfer Buffer 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64666。
T64696	NP-40 Cell Lysis Buffer
	NP-40 Cell Lysis Buffer 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64696。
T7098	BAPTA 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	BAPTA 是非渗透性、选择性的钙离子螯合剂，对 Ca2+的亲和力是 Mg2+的 105 倍。它是一个有价值的研究钙在细胞信号传导中的作用的工具。
T64667	10× SDS-PAGE SDS Running Buffer	Others	Others
	10× SDS-PAGE SDS Running Buffer 是 SDS-PAGE (SDS-变性聚丙烯酰胺凝胶电泳) 10 倍浓缩的缓冲液，主要成分为三羟甲基氨基甲烷(Tris)、甘氨酸(Glycine)和十二烷基硫酸钠(SDS)。
T22274	Bicine Diethanol glycine,Dihydroxyethylglycine,N,N-二羟乙基甘氨酸,N,N-Bis(2-hydroxyethyl)glycine,Diethylolglycine	Others	Others
	Bicine (N,N-Bis(2-hydroxyethyl)glycine) 是一种简单氨基酸甘氨酸的衍生物，用作生物缓冲剂。
T19820	MOPS sodium salt MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt	Others	Others
	MOPS sodium salt (MOPS-Na) 在生物学中常用作缓冲剂。其中MOPS 缓冲液能使哺乳动物细胞培养基的 pH 值保持稳定。
T65287	MES monohydrate	Others	Others
	MES monohydrate 是一种两性离子缓冲液，是一种 PH 稳定试剂，可用于蛋白质纯化和酶测定。
T40645	PIPES 1,4-Piperazinediethanesulfonic acid,1,4-piperazine bis(ethanesulfonic acid),1,4-Piperazinebis(ethanesulfonic acid),PIPES	Others	Others
	PIPES (1,4-Piperazinediethanesulfonic acid) 作为PIPES缓冲液的关键成分，广泛应用于生化领域作为试剂。
T65641	TAPS	Others	Others
	TAPS 是一种生物缓冲液，可以保护溶酶菌结构的完整性，防止其在高温下热变性。TAPS 在 pKa 为 8.1 时，连接蛋白通道活性达到半最大值。
T18890	5-ROX 5-羧基-X-罗丹明,5-Carboxy-X-rhodamine	Others	Others
	5-ROX (5-Carboxy-X-rhodamine) 是罗丹明染料的一种，λexit 为 580 nm (ε=3.6×104M-1cm-1)，λemit 为 604 nm (ϕ=0.94)。
T65636	BIS-TRIS propane BTP	Others	Others
	BIS-TRIS propane (BTP) 是镍基和钴基自旋团簇的新型多齿配体，是一种金属螯合剂。Bis-tris propane 常作为两性离子缓冲液使用，可用于PCR、蛋白质结晶研究和MgATPase 酶活力研究。
T40545	MES 2-Morpholinoethanesulphonic acid,4-Morpholineethanesulfonic acid	Others	Others
	MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid) 是一种两性离子缓冲液，在 pH 值 5.5-7.7 范围内有效。MES 作为一种 Good's 缓冲液，广泛应用于植物培养基、试剂溶液和生理实验中调节 pH 值。
T23378	Sodium phosphate monobasic	Others	Others
	inorganic compound that is used in buffer solutions
T40851	ACES N-氨基甲酰甲基乙磺酸,N-(2-Acetamido)-2-aminoethanesulfonic acid
	ACES, or N-(2-Acetamido)-2-aminoethanesulfonic acid, is a zwitterionic buffer compound. It offers an effective pH range of 6.8-7.2 for various applications.
T40794	HEPPSO
	HEPPSO is a zwitterionic buffer with a working pH range of 7.1-8.5. It exhibits strong copper(II) binding capability and a pK value of 7.84 at a concentration of 2.0 mM.
T60326	CAPSO
	CAPSO 是两性离子生物缓冲液。CAPSO 的有效 pH 范围为 8.9 ~ 10.3。
T40819	MES sodium salt 2-Morpholinoethanesulphonic acid sodium salt
	MES (2-Morpholinoethanesulphonic acid) sodium salt, a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES sodium salt, as one of the Good’s buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.
T61146	PIPES disodium
	PIPES disodium, also known as 1,4-Piperazinediethanesulfonic acid disodium, is a crucial constituent of PIPES buffer agent utilized in the field of biochemistry [1].
T80381	SAAP Fraction 3
	SAAP Fraction 3为具杀菌效能之抗菌肽，能在含锌盐的缓冲液中有效抑杀P. haemolytica。
T70654	Ciprokiren
	Ciprokiren is a renin inhibitor discovered by Roche. Ciprokinen inhibited human renin in a buffer and human plasma with an IC50 of 0.07 and 0.65 nmol/L, respectively. In animal models, acute and chronic administration of ciprokinen lead to a reduction in arterial blood pressure. Development of ciprokinen was discontinued at a preclinical stage.
T83751	PUMA BH3 (human) TFA
	PUMA BH3是一个由p53上调凋亡调节器(PUMA)的BH3域组成的肽，并激活促凋亡蛋白Bak。PUMA BH3与Bak结合（在HEPES和CHAPS缓冲液中的Kds分别为290和26 nM），诱导Bak同源寡聚化和Bak介导的膜透性增加。
T65782	HEPBS	Others	Others
	HEPBS 是一种两性离子生物缓冲剂，其 pH 范围在7.6到9.0之间。HEPBS 可用于细胞的培养和其他细胞实验。
T36369	3,6-diacetoxy Phthalonitrile
	3,6-diacetoxy Phthalonitrile is a fluorescent probe for monitoring intracellular pH by flow cytometry in living cells. It rapidly crosses cell membranes and is cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH), which is excited at UV wavelengths. DCH can be excited at 351 nm, with pH-dependent emission in the range of 450-476 nm (pH 5.0-10.0) using a potassium-based buffer.
T73082	TES sodium
	TES sodium，作为Good's缓冲剂之一，具有pH 6.8-8.2的缓冲范围，其在25°C时的pKa值为7.550。
T37802	Phospho-L-Arginine (lithium salt hydrate)
	Phospho-L-arginine is a phosphorylated form of L-arginine and a highly diffusible, high-energy metabolite and phosphagen involved in energy storage in invertebrates including crustaceans, insects, and Trypanosoma species. In the locust L. migratoria, phospho-L-arginine is found in the flight muscles, where it acts as both a buffer system and shuttle mechanism for high-energy phosphate. Measurement of phospho-L-arginine by 31P-NMR spectroscopy has been used to study invertebrate energy metabolism...
T37095	Quin-2 (potassium salt)
	Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 an...
T37049	monoMICAAc
	monoMICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of monoMICAAc increases. It displays excitation/emission maxima of 425/491, 437/515, and 472/554 nm in hexane, dioxane, and water, respectively. The absorption maximum of monoMICAAc decreases with increasing pH. It displays absorbance/emission maxima of 475/553 and 446/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increa...
T36843	ICAAc
	ICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of ICAAc increases. It displays excitation/emission maxima of 466/553, 431/515, and 418/503 nm in water, dioxane, and hexane, respectively. The absorption maximum of ICAAc decreases with increasing pH. It displays absorption/emission maxima of 470/554 and 428/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increases as pH decre...
T75958	β-Amyloid (22-35) (TFA)
	β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA是β-淀粉样蛋白22-35残基段，具细胞毒性，能影响无血清培养大鼠海马神经元。在中性缓冲液中，此化合物能形成聚集体与典型淀粉样纤维，模拟β-淀粉样蛋白行为。
T35989	CAY10565
	S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0,...
T35988	CAY10564
	S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10564 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.0, ...
T36173	L-Glutathione, oxidized (sodium salt)
	Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The rat...
T35987	CAY10563 CAY10563
	S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10563 is a member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5....
TD0002L	CelRed nucleic acid gel stain 10,000× concentrate in DMSO
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells. Ames test results also show that the mutagenicity of CelRed dye is much less than that of EB. 2) High sensitivi
TD0006	EB Eraser
	The strong EB detoxification agent is specially designed to remove the contaminated product of Ethidium bromide (EB).It can effectively destroy the structure of EB, remove the carcinogenicity of EB, so as to achieve the purpose of cleaning EB pollution.It
T82252	GTPγS tetralithium
	GTPγS (tetralithium) 是一种G蛋白激活剂，能够通过酪氨酸激酶依赖性机制刺激GLUT4的转位，并促进磷脂酶活化和肌动蛋白的聚合，从而可以作为蛋白质抑制蛋白酶介导降解的保护剂。此外，GTPγS (tetralithium) 在研究G蛋白α亚单位功能和激酶活性时可以与其结合使用，并可用作裂解缓冲液中的一个组分。
TD0002	CelRed nucleic acid gel stain 10,000× concentrate in water
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells, and Ames test results also show that the mutagenicity of CelRed dye is much less than EB. 2) High sensitivity:

化合物

Cat.No: T22373

Synonym: ADA buffer,N-(2-Acetamido)-2-Iminodiacetic acid,N-(2-乙酰氨基)-亚氨基二醋酸

Target: Others

Cat.No: T17043

Target: Others

Cat.No: T22606

Target: Others

IP Lysis Buffer

Cat.No: T64722

10× Tris-Glycine Transfer Buffer

Cat.No: T64666

NP-40 Cell Lysis Buffer

Cat.No: T64696

Cat.No: T7098

Synonym: 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸

Target: Reactive Oxygen Species

10× SDS-PAGE SDS Running Buffer

Cat.No: T64667

Target: Others

Cat.No: T22274

Synonym: Diethanol glycine,Dihydroxyethylglycine,N,N-二羟乙基甘氨酸,N,N-Bis(2-hydroxyethyl)glycine,Diethylolglycine

Target: Others

MOPS sodium salt

Cat.No: T19820

Synonym: MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt

Target: Others

MES monohydrate

Cat.No: T65287

Target: Others

Cat.No: T40645

Synonym: 1,4-Piperazinediethanesulfonic acid,1,4-piperazine bis(ethanesulfonic acid),1,4-Piperazinebis(ethanesulfonic acid),PIPES

Target: Others

Cat.No: T65641

Target: Others

Cat.No: T18890

Synonym: 5-羧基-X-罗丹明,5-Carboxy-X-rhodamine

Target: Others

BIS-TRIS propane

Cat.No: T65636

Synonym: BTP

Target: Others

Cat.No: T40545

Synonym: 2-Morpholinoethanesulphonic acid,4-Morpholineethanesulfonic acid

Target: Others

Sodium phosphate monobasic

Cat.No: T23378

Target: Others

Cat.No: T40851

Synonym: N-氨基甲酰甲基乙磺酸,N-(2-Acetamido)-2-aminoethanesulfonic acid

Cat.No: T40794

Cat.No: T60326

MES sodium salt

Cat.No: T40819

Synonym: 2-Morpholinoethanesulphonic acid sodium salt

Cat.No: T61146

SAAP Fraction 3

Cat.No: T80381

Cat.No: T70654

PUMA BH3 (human) TFA

Cat.No: T83751

Cat.No: T65782

Target: Others

3,6-diacetoxy Phthalonitrile

Cat.No: T36369

Cat.No: T73082

Phospho-L-Arginine (lithium salt hydrate)

Cat.No: T37802

Quin-2 (potassium salt)

Cat.No: T37095

Cat.No: T37049

Cat.No: T36843

β-Amyloid (22-35) (TFA)

Cat.No: T75958

Cat.No: T35989

Cat.No: T35988

L-Glutathione, oxidized (sodium salt)

Cat.No: T36173

Cat.No: T35987

Synonym: CAY10563

CelRed nucleic acid gel stain *10,000× concentrate in DMSO*

Cat.No: TD0002L

Cat.No: TD0006

GTPγS tetralithium

Cat.No: T82252

CelRed nucleic acid gel stain *10,000× concentrate in water*

Cat.No: TD0002

Cat. No.	Product Name	Target	Signaling Pathways
T12952	Sodium citrate dihydrate Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠	Antibacterial	Microbiology/Virology
	Sodium citrate dihydrate (Trisodium citrate dihydrate) 是一种抗凝血剂，也用为缓冲剂和食品防腐剂。
T19284	Dimethylmalonic acid 2,2-Dimethylmalonic acid	Endogenous Metabolite	Metabolism
	Dimethylmalonic acid（2,2-Dimethylmalonic acid）是人血清中的短链二羧酸，可用于预防或延缓鱼肌动球蛋白在冷冻缓冲溶液（pH 7）中的变性。
T2719	Succinic acid Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid	Endogenous Metabolite	Metabolism
	Succinic acid (1,2-Ethanedicarboxylic acid) 是无氧代谢的发酵产物，也是三羧酸循环的中间产物。
T65128	Tartaric acid disodium dihydrate Disodium L-(＋)-Tartrate Dihydrate	Phosphatase; Endogenous Metabolite	Metabolism
	Tartaric acid disodium dihydrate (Disodium L-(＋)-Tartrate Dihydrate) 常用来制作分子生物学和细胞培养中的缓冲液,。Tartaric acid disodium dihydrate 是酸性磷酸酶抑制剂, 可增加秋水仙碱结合 tubulin1的概率。
T4915	β-Glycerophosphate disodium salt hydrate	Phosphatase; Endogenous Metabolite	Metabolism
	β-Glycerophosphate disodium salt hydrate 是一种磷酸酶抑制剂，是内源性代谢产物的一种。

天然产物

Sodium citrate dihydrate

Cat.No: T12952

Synonym: Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠

Target: Antibacterial

Dimethylmalonic acid

Cat.No: T19284

Synonym: 2,2-Dimethylmalonic acid

Target: Endogenous Metabolite

Cat.No: T2719

Synonym: Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid

Target: Endogenous Metabolite

Tartaric acid disodium dihydrate

Cat.No: T65128

Synonym: Disodium L-(＋)-Tartrate Dihydrate

Target: Phosphatase, Endogenous Metabolite

β-Glycerophosphate disodium salt hydrate

Cat.No: T4915

Target: Phosphatase, Endogenous Metabolite

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