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Search Results for " articular cartilage "

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抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T9711 OGT-IN-2

Others Others
OGT-IN-2 是 OGT 抑制剂,抑制 sOGT 和 ncOGT 的 IC50分别为 30 μM 和 53 μM。它在关节疾病方面有研究的价值,如关节软骨疾病、骨关节炎。
T5359 RCGD423

Interleukin Immunology/Inflammation
RCGD423 是一种gp130调节剂,能阻断关节软骨的退化,并诱导其修复。
T71420 RO314724

RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.

化合物

OGT-IN-2
Cat.No: T9711
Synonym:
Target: Others
RCGD423
Cat.No: T5359
Synonym:
Target: Interleukin
RO314724
Cat.No: T71420
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T5223 Heneicosanoic acid

二十一碳酸,Heneicosylic Acid,C21:0

Others; Endogenous Metabolite Metabolism; Others
Heneicosanoic acid (C21:0) 是广泛存在于动植物中的长链饱和脂肪酸。

天然产物

Heneicosanoic acid
Cat.No: T5223
Synonym: 二十一碳酸,Heneicosylic Acid,C21:0
Target: Others, Endogenous Metabolite
TargetMol Loading
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