Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40711 |
H-D-Phe-Pip-Arg-pNA dihydrochloride
S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride |
Others | Others |
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation. | |||
T22323 |
Enoxaparin sodium
|
Thrombin | Proteases/Proteasome |
Enoxaparin sodium 是一种低分子量肝素 (LMWH),已获得美国 FDA 批准,可用于医疗管理的 ST 段心肌梗死 (STEMI) 或 STEMI 及随后的经皮冠状动脉介入治疗 (PCI) 患者。它与抗凝血酶结合并增强其作用,并抑制凝血因子 XIa、IXa、Xa 和 IIa(凝血酶),从而防止血栓形成。 | |||
T68002 |
Naroparcil
|
Thrombin | Proteases/Proteasome |
Naroparcil 是一种可口服的硫代苷类化合物,是一种 4-甲基伞形 β-D-木糖苷类似物,在静脉血栓形成(颈静脉)的Wessler淤滞模型中显示出抗血栓形成作用。Naroparcil 增强了凝血酶/肝素辅因子II复合物的形成,诱导了处理兔血浆中硫酸皮肤素样物质的出现,但减少了与(125I)-人α-凝血酶孵育的血浆中的凝血酶/抗凝血酶III复合物的形成。 | |||
T64262 |
Heparin Lithium salt
|
||
Heparin Lithium salt 是一种抗凝剂,能够可逆的结合抗凝血酶III (ATIII)。Heparin Lithium salt 明显阻碍外泌体-细胞相互作用。 | |||
T16377 |
Odiparcil
SB-424323 |
Thrombin | Proteases/Proteasome |
Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antithrombotic activity associated with a reduced risk of adverse bleeding events. | |||
T39066 |
H-D-Phe-Pip-Arg-pNA hydrochloride
S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride |
||
H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process. |