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抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7785	T-1105	Influenza Virus	Microbiology/Virology
	T-1105 是 T-705 的结构类似物，是一种广谱病毒聚合酶抑制剂，在转化为核糖核苷三磷酸代谢物后抑制 RNA 病毒的聚合酶，有抗病毒活性。
T12962	Sofosbuvir impurity G	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity G 是 Sofosbuvir 的非对映异构体，是 Sofosbuvir 的杂质。其中 Sofosbuvir 能够抑制 HCVRNA 的复制，具有抗丙型肝炎病毒作用。
T13075	T-705RTP	Others	Others
	T-705RTP is a selective and GTP-competitive of influenza virus RNA polymerase(IC50 of 0.14 μM and a Ki of 1.52 μM), has potent anti-influenza virus activity.
T12966	Sofosbuvir impurity K	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12969	Sofosbuvir impurity N	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12965	Sofosbuvir impurity J	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12964	Sofosbuvir impurity I	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T13075L	T-705RTP sodium	Others	Others
	T-705RTP sodium is a selective and GTP-competitive of influenza virus RNA polymerase(IC50 of 0.14 μM and a Ki of 1.52 μM), has potent anti-influenza virus activity.
T12956	Sofosbuvir impurity A	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T12968	Sofosbuvir impurity M	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12963	Sofosbuvir impurity H	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is a diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12967	Sofosbuvir impurity L	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12959	Sofosbuvir impurity D	Others	Others
	Sofosbuvir impurity D is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T62888	Influenza A virus-IN-7
	Influenza A virus-IN-7 (compound 16r) 是一种有效的、口服具有活力的甲型流感病毒抑制剂 (IC50: 3.43 μM, CC50>100 μM)。Influenza A virus-IN-7 具有抗 IAV 作用，细胞毒性低，对病毒 RNA 的转录和复制表现出抑制作用。
T12960	Sofosbuvir impurity E	Others	Others
	Sofosbuvir impurity E is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T12954	Sofosbuvir 13CD3 GS-7977 13CD3,PSI-7977 13CD3	Others	Others
	Sofosbuvir 13CD3 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity.
T12957	Sofosbuvir impurity B	Others	Others
	Sofosbuvir impurity B is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity.
T80760	XSJ2-46	Influenza Virus	Microbiology/Virology
	XSJ2-46，一种5'-氨基NI类似物，表现为有效的抗病毒药物，尤其针对Zika病毒。它通过抑制RNA依赖性RNA聚合酶（RdRp），展示出其活性，具有8.78 μM的IC50值。
T12958	Sofosbuvir impurity C	Others	Others
	Sofosbuvir impurity C is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T12955	Sofosbuvir D6 PSI-7977 D6,GS-7977 D6	Others	Others
	Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
T14493	Balapiravir R1626,Ro 4588161	Others	Others
	Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (m

化合物

Cat.No: T7785

Target: Influenza Virus

Sofosbuvir impurity G

Cat.No: T12962

Target: HCV Protease

Cat.No: T13075

Target: Others

Sofosbuvir impurity K

Cat.No: T12966

Target: HCV Protease

Sofosbuvir impurity N

Cat.No: T12969

Target: HCV Protease

Sofosbuvir impurity J

Cat.No: T12965

Target: HCV Protease

Sofosbuvir impurity I

Cat.No: T12964

Target: HCV Protease

T-705RTP sodium

Cat.No: T13075L

Target: Others

Sofosbuvir impurity A

Cat.No: T12956

Target: HCV Protease

Sofosbuvir impurity M

Cat.No: T12968

Target: HCV Protease

Sofosbuvir impurity H

Cat.No: T12963

Target: HCV Protease

Sofosbuvir impurity L

Cat.No: T12967

Target: HCV Protease

Sofosbuvir impurity D

Cat.No: T12959

Target: Others

Influenza A virus-IN-7

Cat.No: T62888

Sofosbuvir impurity E

Cat.No: T12960

Target: Others

Sofosbuvir 13CD3

Cat.No: T12954

Synonym: GS-7977 13CD3,PSI-7977 13CD3

Target: Others

Sofosbuvir impurity B

Cat.No: T12957

Target: Others

Cat.No: T80760

Target: Influenza Virus

Sofosbuvir impurity C

Cat.No: T12958

Target: Others

Cat.No: T12955

Synonym: PSI-7977 D6,GS-7977 D6

Target: Others

Cat.No: T14493

Synonym: R1626,Ro 4588161

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3376	Cynaroside 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside	Others; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Cynaroside (Luteolin 7-O-Glucoside) 是一个抗氧化类黄酮。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 32 nM。

天然产物

Cat.No: T3376

Synonym: 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside

Target: Others, Influenza Virus, DNA/RNA Synthesis

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