Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78361 |
Penicillin amidase
Penicillin acylase |
||
Penicillin amidase(Penicillin acylase)是裂解青霉素酰基侧链的酶,用于生产6-氨基青霉烷酸,以及拆分外消旋混合物,合成肽和半合成β-内酰胺类抗生素。 | |||
T8533 |
ML318
|
Others; Antibiotic | Microbiology/Virology; Others |
ML318 是 PvdQ 酰基转移酶的联芳基腈抑制剂,可以结合在酰基结合位点上,IC50为 20 nM。它抑制铜绿假单胞菌的 IC50为 19 μM。它可防止嘧啶的产生并限制了铜绿假单胞菌在铁限制条件下的生长。 | |||
T75396 | Sphingolipid ceramide N-deacylase (SCDase) | ||
Sphingolipid ceramide N-deacylase (SCDase) 催化糖鞘脂中的脂肪酸与鞘氨醇碱基间的N-酰基键断裂,进而生成溶血糖鞘脂。 | |||
T36024 |
FR179642 (hydrate)
FR179642 (hydrate) |
||
FR179642 is the cyclic peptide nucleus of the lipopeptide antifungal FR901379 and an intermediate in the synthesis of the echinocandin antifungal FK463 .1,2 1.Tomishima, M., Ohki, H., Yamada, A., et al.FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activityJ. Antibiot. (Tokyo)52(7)674-676(1999) 2.Ueda, S., Shibata, T., Ito, K., et al.Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907J. Antibiot. (Tokyo)64(2)169-175(2011) |