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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17363 |
β-Naphthoflavone-CH2-OH
β-NF-CH2-OH |
Others | Others |
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1]. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2O2744 |
alpha-Naphthoflavone
苯并黄素;α-萘黄酮;7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮 |
Aromatase | Endocrinology/Hormones |
alpha-Naphthoflavone (7,8-benzoflavone) 是合成的黄酮类化合物,是一种竞争性芳香酶抑制剂,其IC50=0.5 μM,Ki=0.2 μM。 |