Cat. No. | Product Name | Target | Signaling Pathways |
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T61762 |
Zika virus-IN-3
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Zika virus-IN-3 (Compd 7) 是Zika 病毒的抑制剂,其EC50值为 3.4 μM。 | |||
T25130 |
Azaribine
2',3',5'-Tri-O-acetyl-6-azauridine,NSC 67239 |
Antiviral | Immunology/Inflammation |
Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) 是一种乳清碱单磷酸脱羧酶 (OMPD) 抑制剂,具有广谱的抗病毒活性,可抑制病毒基因组复制和基因转录。Azaribine 可用于研究寨卡病毒 (ZIKV)感染,可用于研究银屑病关节炎和蕈样肉芽肿。 | |||
T61953 |
Zika virus-IN-2
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Zika virus-IN-2 (Compd 3) 是Zika 病毒的抑制剂(EC50= 7.4 μM)。 | |||
T73292 |
ZIKV-IN-3
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ZIKV-IN-3, 一个穿心莲内酯衍生物,作为有效的ZIKV NS5甲基转移酶(MTase)抑制剂,展示了18.34 μM的IC50值。该化合物能抑制ZIKV的复制与感染,适用于寨卡病毒(ZIKV)的研究。 | |||
T21978 |
p-nitro-Pifithrin-α
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p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4]. |