Cat. No. | Product Name | Target | Signaling Pathways |
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T80722 |
Z-LVG
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Z-LVG为一种不可逆半胱氨酸蛋白酶抑制剂,作为半胱抑素C的三肽衍生物,其可抑制病毒复制,应用于病毒相关疾病研究。 | |||
T38130 |
Z-LVG-CHN2
Z-Leu-Val-Gly-diazomethylketone |
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The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain. | |||
T78119 |
Z-L(D-Val)G-CHN2
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HSV | Microbiology/Virology |
Z-L(D-Val)G-CHN2(即Z-LVG-CHN2)是半胱氨酸蛋白酶抑制剂的异构体,作为一种三肽衍生物,模仿了人体半胱氨酸蛋白酶结合中心的部分结构。它可以抑制HSV,并且能有效阻断SARS-COV-2的3CL pro蛋白酶,从而抑制病毒活性(EC50=190 nM),但对脊髓灰质炎病毒复制无显著作用。 |