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Cat. No. Product Name Target Signaling Pathways
T23524 W-84 dibromide

HDMPPA

AChR Neuroscience
W-84 dibromide (HDMPPA) 是 M2胆碱受体的强变构调节剂,是一种非竞争性毒蕈碱乙酰胆碱受体拮抗剂,具有变构效应。它联合阿托品时,可有效地防止有机磷中毒。它阻碍 [3H]N-甲基东莨菪碱解离,能稳定胆碱能拮抗剂-受体复合物。
T28521 Retelliptine

SR-95325B (diHCl),NSC-D-626717-W,SR-95325A (dimaleate),BD-84

Retelliptine, a DNA topoisomerase II inhibitor, is used potentially for the treatment of cancer.
T38111 Dimethyl-W84 (dibromide)

Dimethyl-W84 (dibromide)

Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM.
T38385 IT-143B

IT-143B is a bacterial metabolite that has been found in S. iakyrus.1 It inhibits the proliferation of OS-RC-2 and ACHN cancer cells (IC50s = 22 and 98 μM, respectively). |1. Li, K., Liang, Z., Chen, W., et al. Iakyricidins A-D, antiproliferative piericidin analogues bearing a carbonyl group or cyclic skeleton from Streptomyces iakyrus SCSIO NS104. J. Org. Chem. 84(19), 12626-12631 (2019).
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...

化合物

W-84 dibromide
Cat.No: T23524
Synonym: HDMPPA
Target: AChR
Retelliptine
Cat.No: T28521
Synonym: SR-95325B (diHCl),NSC-D-626717-W,SR-95325A (dimaleate),BD-84
Target:
Dimethyl-W84 (dibromide)
Cat.No: T38111
Synonym: Dimethyl-W84 (dibromide)
Target:
IT-143B
Cat.No: T38385
Synonym:
Target:
HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
TargetMol Loading
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