Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17881 |
(S,R,S)-AHPC-C10-NH2
VH032-C10-NH2 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) 包含基于 (S,R,S)-AHPC 的VHL 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)。用于 BET 的靶向 PROTAC 的合成。 | |||
T18661 |
(S,R,S)-AHPC-C10-NH2 dihydrochloride
VH032-C10-NH2 dihydrochloride,VH032-linker 10,(S,R,S)-AHPC-C10-NH2二盐酸盐,VH032 amide-alkylC10-amine |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) 包含基于 (S,R,S)-AHPC 的VHL 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,用于合成 BET 的靶向 PROTAC。 | |||
T17926 |
(S,R,S)-AHPC-PEG6-C4-Cl
VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl |
Others | Others |
(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. | |||
T17910 |
(S,R,S)-AHPC-PEG2-C4-Cl
E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl |
Others | Others |
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. |