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Cat. No.	Product Name	Target	Signaling Pathways
T35478	cis VH 032, amine dihydrochloride (S,S,S)-AHPC
	cis VH 032, amine dihydrochloride ((S,S,S)-AHPC) 是功能性 VHL ligand VH 032, amine 的阴性对照.
T29106	VH032 VH-032,VH 032	Ligand for E3 Ligase	PROTAC
	VH032通常用作 PROTAC 的前体，作为 E3泛素连接酶组件连接 VHL，是一种与 KdPROTACs 相互作用的 VHL/HIF-1α抑制剂，作为von Hippel-Lindau (VHL)的配体招募VHL 蛋白。
T36277	VH 032 amide-alkylC2-acid VH 032 amide-alkylC2-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36278	VH 032 amide-alkylC3-acid VH 032 amide-alkylC3-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for research and development; incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules.
T36266	VH 032 amide-PEG3-amine VH 032 amide-PEG3-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 1 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36282	VH 032 amide-alkylC7-amine VH 032 amide-alkylC7-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36283	VH 032 amide-alkylC8-acid VH 032 amide-alkylC8-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36281	VH 032 amide-alkylC5-amine VH 032 amide-alkylC5-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 13 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36279	VH 032 amide-alkylC3-amine VH 032 amide-alkylC3-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl C3 linker and terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36267	VH 032 amide-PEG4-amine VH 032 amide-PEG4-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36280	VH 032 amide-alkylC4-acid VH 032 amide-alkylC4-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36285	VH 032 amide-PEG1-acid VH 032 amide-PEG1-acid
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36268	VH 032 Linker 3 (hydrate)
	VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 . N/A
T36272	VH032-OH VH 032, phenol
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T17877	VH032-cyclopropane-F VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101	Others; Ligand for E3 Ligase	Others; PROTAC
	VH032-cyclopropane-F (Phenolic VH101) 是基于 VH032 的 VHL 配体。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子，如 PROTAC 1。PROTAC 1 是 SMARCA2 和 SMARCA4 的部分降解剂。
T41171	BODIPY FL VH032
	BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable...
T36269	(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride VH 032 phenol-alkylC4-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 1 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36284	(S,R,S)-AHPC-C8-NH2 dihydrochloride VH 032 amide-alkylC8-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36265	(S,R,S)-AHPC-PEG3-propionic acid VH 032 amide-PEG3-acid
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36270	(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride VH 032 phenol-alkylC6-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T17230	VH032-PEG3-acetylene	Others	Others
	VH032-PEG3-acetylene is a synthesized conjugate compound consisting of a VH032-based VHL ligand and a linker, designed for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].
T36264	(S,R,S)-AHPC-PEG1-NH2 dihydrochloride VH 032 amide-PEG1-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 9 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T18600	VH032 thiol VHL ligand 6	Others	Others
	VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
T83954	VH 032 amide-alkylC7-acid (S,R,S)-AHPC-amido-C7-acid
	VH 032 amide-alkylC7-acid 是一种用于PROTAC研究与开发的功能化Von-Hippel-Lindau蛋白配体(VHL)，结合了E3连接酶配体和具有末端羧酸的alkylC7连接物，便于与目标蛋白配体偶联。该化合物是为PROTAC研发设计的一系列功能化工具分子之一。
T17996	VH032-PEG5-C6-Cl HaloPROTAC 2	Others	Others
	VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T18602	VH032-thiol-C6-NH2 VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29	Others	Others
	VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonly utilized in PROTAC technology.
T18667	(S,R,S)-AHPC-C5-COOH VH032-C5-COOH	Others	Others
	(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases[1].

化合物

cis VH 032, amine dihydrochloride

Cat.No: T35478

Synonym: (S,S,S)-AHPC

Cat.No: T29106

Synonym: VH-032,VH 032

Target: Ligand for E3 Ligase

VH 032 amide-alkylC2-acid

Cat.No: T36277

Synonym: VH 032 amide-alkylC2-acid

VH 032 amide-alkylC3-acid

Cat.No: T36278

Synonym: VH 032 amide-alkylC3-acid

VH 032 amide-PEG3-amine

Cat.No: T36266

Synonym: VH 032 amide-PEG3-amine

VH 032 amide-alkylC7-amine

Cat.No: T36282

Synonym: VH 032 amide-alkylC7-amine

VH 032 amide-alkylC8-acid

Cat.No: T36283

Synonym: VH 032 amide-alkylC8-acid

VH 032 amide-alkylC5-amine

Cat.No: T36281

Synonym: VH 032 amide-alkylC5-amine

VH 032 amide-alkylC3-amine

Cat.No: T36279

Synonym: VH 032 amide-alkylC3-amine

VH 032 amide-PEG4-amine

Cat.No: T36267

Synonym: VH 032 amide-PEG4-amine

VH 032 amide-alkylC4-acid

Cat.No: T36280

Synonym: VH 032 amide-alkylC4-acid

VH 032 amide-PEG1-acid

Cat.No: T36285

Synonym: VH 032 amide-PEG1-acid

VH 032 Linker 3 (hydrate)

Cat.No: T36268

Cat.No: T36272

Synonym: VH 032, phenol

VH032-cyclopropane-F

Cat.No: T17877

Synonym: VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101

Target: Others, Ligand for E3 Ligase

BODIPY FL VH032

Cat.No: T41171

(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride

Cat.No: T36269

Synonym: VH 032 phenol-alkylC4-amine

(S,R,S)-AHPC-C8-NH2 dihydrochloride

Cat.No: T36284

Synonym: VH 032 amide-alkylC8-amine

(S,R,S)-AHPC-PEG3-propionic acid

Cat.No: T36265

Synonym: VH 032 amide-PEG3-acid

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride

Cat.No: T36270

Synonym: VH 032 phenol-alkylC6-amine

VH032-PEG3-acetylene

Cat.No: T17230

Target: Others

(S,R,S)-AHPC-PEG1-NH2 dihydrochloride

Cat.No: T36264

Synonym: VH 032 amide-PEG1-amine

Cat.No: T18600

Synonym: VHL ligand 6

Target: Others

VH 032 amide-alkylC7-acid

Cat.No: T83954

Synonym: (S,R,S)-AHPC-amido-C7-acid

VH032-PEG5-C6-Cl

Cat.No: T17996

Synonym: HaloPROTAC 2

Target: Others

VH032-thiol-C6-NH2

Cat.No: T18602

Synonym: VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29

Target: Others

(S,R,S)-AHPC-C5-COOH

Cat.No: T18667

Synonym: VH032-C5-COOH

Target: Others

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