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6

抑制剂 & 化合物

3

天然产物

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Cat. No. Product Name Target Signaling Pathways
T37375 Uridine-3'-monophosphate (sodium salt)

Uridine-3'-monophosphate is a nucleoside used in the biochemical synthesis of ribothymidine-3'-phosphate. It has been used as a bioavailable source of uridine in research studies designed to enhance learning and memory.
T74046 D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine

D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine,即1-磷酸核糖,作为核苷酸合成的关键中间体,在5-氟尿嘧啶(FUra)的磷酸化过程中,被尿苷磷酸化酶催化转化为核苷。
T83823 Sp-Uridine-5'-O-(1-thiotriphosphate) sodium

Sp-UTP-α-S

Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) 是 purinergic Y2 (P2Y2) 和 P2Y4 受体的核苷酸激动剂。它在表达 purinergic P2Y2 或 P2Y4 受体的 1321N1 星形胶质瘤细胞中诱导肌醇磷酸累积(EC50s 分别为 14 和 81 µM)。
T83822 Rp-Uridine-5'-O-(1-thiotriphosphate) sodium

Rp-UTP-α-S

Rp-Uridine-5'-O-(1-thiotriphosphate)(Rp-UTP-α-S)是一种核苷酸激动剂,针对嘌呤P2Y2和P2Y4受体。在表达P2Y2或P2Y4受体的1321N1星形胶质细胞中,它能够促进肌醇磷酸的积累(EC50s分别为5.4 和27 µM)。
T83840 Uridine-5'-O-(3-thiotriphosphate) sodium

UTP-γ-S

Uridine-5'-O-(3-thiotriphosphate) (UTP-γ-S) 是UTP的一种抗水解衍生物,是嘌呤P2Y2受体的激动剂。在表达人类P2Y2受体的1321N1星形胶质瘤细胞中,其可诱导肌醇磷酸盐的形成(EC50 = 240 nM),并且在来自囊性纤维化患者的原代鼻上皮细胞中以浓度依赖的方式诱导氯离子分泌。UTP-γ-S在分离的人类冠状动脉中诱导血管收缩(EC50 = 25.1 µM)。
T68656 Brivudine monophosphate

Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator...

化合物

Uridine-3'-monophosphate (sodium salt)
Cat.No: T37375
Synonym:
Target:
D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
Cat.No: T74046
Synonym:
Target:
Sp-Uridine-5'-O-(1-thiotriphosphate) sodium
Cat.No: T83823
Synonym: Sp-UTP-α-S
Target:
Rp-Uridine-5'-O-(1-thiotriphosphate) sodium
Cat.No: T83822
Synonym: Rp-UTP-α-S
Target:
Uridine-5'-O-(3-thiotriphosphate) sodium
Cat.No: T83840
Synonym: UTP-γ-S
Target:
Brivudine monophosphate
Cat.No: T68656
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4718 Uridine 5'-monophosphate

Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid

Others; Endogenous Metabolite Metabolism; Others
Uridine 5'-monophosphate (Uridylic acid) 是一种单磷酸盐形式的尿嘧啶核苷酸,能够由从头途径或体内核苷酸和核酸的降解产物获得,是哺乳动物乳中的主要核苷酸类似物。
T38251 L-Uridine

Nucleoside Antimetabolite/Analog; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
L-Uridine 是从Polyporaceae fungus Poria cocos (Schw.)分离得到的正常 RNA 成分中的 D-尿苷的对映异构体,属于一种核苷,可充当核苷磷酸转移酶的磷酸受体。L-Uridine 具有潜在的抗病毒活性。
T4922 Uridine 5′-triphosphate tris salt

尿苷-5′-三磷酸酯 三羟甲基氨基甲烷盐,Uridine 5'-triphosphoric acid

Others; Endogenous Metabolite Metabolism; Others
Uridine 5′-triphosphate tris salt (Uridine 5'-triphosphoric acid) 是 P2Y 受体的激动剂,已用于研究细胞内 Ca2+ 的浓度,以及用于体外激酶测定的磷酸盐供体。

天然产物

Uridine 5'-monophosphate
Cat.No: T4718
Synonym: Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid
Target: Others, Endogenous Metabolite
L-Uridine
Cat.No: T38251
Synonym:
Target: Nucleoside Antimetabolite/Analog, Antibiotic
Uridine 5′-triphosphate tris salt
Cat.No: T4922
Synonym: 尿苷-5′-三磷酸酯 三羟甲基氨基甲烷盐,Uridine 5'-triphosphoric acid
Target: Others, Endogenous Metabolite
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