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Search Results for " tunicamycin "

11

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T38082	Tunicamycin 15:1 Mixture
	Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contain a 15-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 15:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 15:1 withiso,anteiso, or a mixture ofisoandanteisobranching configurations inhibit bacteria...
T38083	Tunicamycin 17:1 Mixture
	Tunicamycin 17:1 is a mixture of tunicamycin structural isomers that contain a 17-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 17:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 17:1 withisooranteisobranching configurations inhibits bacterial phospho-MurNAc-pentapeptid...
T38081	Tunicamycin 14:1 Mixture
	Tunicamycin 14:1 is a mixture of tunicamycin structural isomers that contain a 14-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 14:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) in Streptomyces and directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 14:1 with the iso branching configuration inhibits bacterial phospho-MurNAc-pentapeptide ...
T124449	Tunicamycin VII
	Tunicamycin VII 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124449，CAS号为 66081-36-5。
T124448	Tunicamycin X
	Tunicamycin X 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124448，CAS号为 66081-38-7。
T124297	Tunicamycin VIII
	Tunicamycin VIII 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124297，CAS号为 73942-07-1。
T16550	PKR-IN-C16	Others	Others
	PKR-IN-C16 是一种特异性蛋白激酶抑制剂。它能够抑制 PKR 的自磷酸化，解除 PKR 在原代神经元细胞培养中诱导的翻译阻断。
T36475	TunR2
	TunR2 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtiliswhen used at a concentration of 0.4 μg/ml. Unlike tunicamycin, TunR2 is non-toxic toS. cerevisiae(MIC = >10 μg/ml) and does not inhibit glycosylation in a protein N-glycosylation assay. TunR2 also has reduced antiproliferative activity against MDA-MB-231 and CHO cells compared wi...
T36474	TunR1
	TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtiliswhen used at a concentration of 0.4 μg/ml. TunR1 (5 μg/ml) is cytotoxic to MDA-MB-231 breast cancer cells and non-cancerous CHO cells. Unlike tunicamycin, TunR1 does not inhibit glycosylation in a protein N-glycosylation assay. 1.Price, N.P., Hartman, T.M., Li, J., et al.Modified...
T36328	Termitomycamide B
	Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson's, Alzheimer's, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid i...
T36570	KUS121
	KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50 μM, respectively. KUS121 (100 μM) inhibits ATP depletion and cell death induced by oxygen-glucose deprivation (OGD) in rat primary cortical neurons in anin vitromodel of cerebral ischemia.2It red...

化合物

Tunicamycin 15:1 Mixture

Cat.No: T38082

Tunicamycin 17:1 Mixture

Cat.No: T38083

Tunicamycin 14:1 Mixture

Cat.No: T38081

Tunicamycin VII

Cat.No: T124449

Tunicamycin X

Cat.No: T124448

Tunicamycin VIII

Cat.No: T124297

Cat.No: T16550

Target: Others

Cat.No: T36475

Cat.No: T36474

Termitomycamide B

Cat.No: T36328

Cat.No: T36570

Cat. No.	Product Name	Target	Signaling Pathways
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
T38299	Tunicamycin V
	Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns. References

天然产物

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Tunicamycin V

Cat.No: T38299

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