Cat. No. | Product Name | Target | Signaling Pathways |
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T73307 |
TrkA-IN-4
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TrkA-IN-4 是一种有效和具有口服活性的 TrkA 变构抑制剂,是TrkA-IN-3 的前药。TrkA-IN-4 显示出有效的抗伤害作用。 | |||
T17169 |
Trk-IN-4
PF-6683324 isomer |
Trk receptor | Tyrosine Kinase/Adaptors |
Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and 1.1 nM for TrkA, TrkB, and TrkC, respectively). | |||
T37582 |
Ganglioside GM1 Mixture (ovine) (ammonium salt)
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Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i... |