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7

抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T29011 Triiodothyronine Sulfate

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
Triiodothyronine sulfate 是一种甲状腺激素三碘甲状腺原氨酸的主要代谢物,是一种甲状腺激素,与 β1 甲状腺激素受体结合并激活其特性。
T1669 Liothyronine sodium

3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel

Thyroid hormone receptor(THR) Endocrinology/Hormones
Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) 是甲状腺激素,能够结合并激活 β1 甲状腺激素受体。
T1669L Liothyronine HCl

Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine

Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.
T7578 REVERSE T3

碘塞罗宁,3,3',5'-triiodo-L-thyronine

Thyroid hormone receptor(THR) Endocrinology/Hormones
Reverse T3 (3,3',5'-triiodo-L-thyronine) 是由甲状腺素原脱碘后产生的甲状腺激素。它可抑制由其它甲状腺激素类似物引起的新生大鼠心肌细胞中钠电流增加的作用。
T25411 Fenclofenac

R 67408,Rx 67408,R67408,Flenac

Fenclofenac is a non-steroidal anti-inflammatory agent that competitively supresses the binding of thyroxine(T4) and triiodothyronine (T3) by thyroxine-binding globulin(TBG).
T15699 L-Thyroxine sodium salt pentahydrate

左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物

Thyroid hormone receptor(THR) Endocrinology/Hormones
L-Thyroxine sodium salt pentahydrate (Levothyroxine) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。
T35712 Debutyldronedarone hydrochloride

SR35021 hydrochloride

N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbutyl dronedarone inhibits the binding of 3,3’,5-triiodo-L-thyronine to the thyroid hormone receptors TRα1and TRβ1(IC50s = 59 and 280 μM for the chicken and human receptors, respectively).1It inhibits CYP2J2-mediated formation of 14,15-EET from arachidonic acid and soluble epoxide h...

化合物

Triiodothyronine Sulfate
Cat.No: T29011
Synonym:
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Liothyronine sodium
Cat.No: T1669
Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel
Target: Thyroid hormone receptor(THR)
Liothyronine HCl
Cat.No: T1669L
Synonym: Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine
Target:
REVERSE T3
Cat.No: T7578
Synonym: 碘塞罗宁,3,3',5'-triiodo-L-thyronine
Target: Thyroid hormone receptor(THR)
Fenclofenac
Cat.No: T25411
Synonym: R 67408,Rx 67408,R67408,Flenac
Target:
L-Thyroxine sodium salt pentahydrate
Cat.No: T15699
Synonym: 左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物
Target: Thyroid hormone receptor(THR)
Debutyldronedarone hydrochloride
Cat.No: T35712
Synonym: SR35021 hydrochloride
Target:
Cat. No. Product Name Target Signaling Pathways
T1653 Liothyronine

Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
Liothyronine (Tresitope) 是一种有效的甲状腺激素,能够激活 β1 甲状腺激素受体 (TRβ1)。
T0864 L-Thyroxine

Levothyroxine,NSC 36397,L-甲状腺素,T4

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
L-Thyroxine (NSC 36397) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。在 DIO 酶作用下,L-Thyroxine (NSC 36397) 转化成具有生物特性的三碘甲状腺氨酸(T3)。
T13060 T3 Acyl glucuronide

Others Others
T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

天然产物

Liothyronine
Cat.No: T1653
Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
L-Thyroxine
Cat.No: T0864
Synonym: Levothyroxine,NSC 36397,L-甲状腺素,T4
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
T3 Acyl glucuronide
Cat.No: T13060
Synonym:
Target: Others
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