Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3516 |
EDO-S101
Tinostamustine,Minomustine |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
EDO-S101 (Tinostamustine) 是一种泛 HDAC 抑制剂,IC50为 6 nM,对 HDAC1、HDAC2 和 HDAC3 的 IC50 值分别为 9、9 和 25 nM。 | |||
T70190 |
Tinostamustine HCl
|
||
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents. | |||
T70189 | Navoximod phosphate | ||
Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic. |