Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18831 |
Thalidomide-propargyl
|
Others; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-propargyl 是一种基于 Thalidomide 的 Cereblon 配体,可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接,得到含 IMiD 的 PROTAC。 | |||
T9389 |
Thalidomide-PEG4-Propargyl
Thalidomide-O-PEG4-Propargyl |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,。 | |||
T18823 | Thalidomide-O-amido-PEG4-propargyl | Others | Others |
Thalidomide-O-amido-PEG4-propargyl is a polyethylene glycol (PEG)-based linker employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1]. | |||
T18826 |
Thalidomide-O-PEG2-propargyl
E3 ligase Ligand-Linker Conjugates 32 |
Others | Others |
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1]. | |||
T16603 |
Propargyl-PEG2-OH
|
Others | Others |
Propargyl-PEG2-OH is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed for efficient synthesis of Thalidomide-O-PEG2-propargyl. | |||
T17125 | Tos-PEG2-O-Propargyl | Others | Others |
Tos-PEG2-O-Propargyl is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, commonly employed for the synthesis of Thalidomide-O-PEG2-propargyl[1]. |