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Cat. No.	Product Name	Target	Signaling Pathways
T13078	Tankyrase-IN-2	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively
T63508	OM-153
	OM-153 是 tankyrase 的有效抑制剂，能够作用于 tankyrase 1 (IC50: 13 nM) 和 tankyrase 2 (IC50: 2 nM)，且对 COLO 320DM 中的 WNT/β-连环蛋白信号传导和增殖具有抑制作用。
T72922	TNKS1/2-IN-1
	TNKS1/2-IN-1是一种针对tankyrase TNKS1/2的高效抑制剂，其pIC50值介于7.1至8.2之间。该化合物主要用于癌症、纤维化及其他高增殖性疾病的研究领域。
T69955	JPI-547 HCl
	JPI 547, also known as NOV 1402, is an oral inhibitor of PARP 1/2 and Tankyrase 1/2. JPI-547 demonstrated anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and immune checkpoint inhibitors.
T70138	AZ0108
	AZ0108 is an orally bioavailable, potent PARP1,2,6 inhibitor that potently inhibits centrosome clustering and is suitable for in vivo efficacy and tolerability studies. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. AZ0108 is more selective in its enzyme inhibition profile and effects on cellular pathways and phenotypes. Specifically, AZ0108 inhibits PARPs 1, 2, and 6 with approxi...