Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12777 |
RTC-5
TRC-382 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
RTC-5 (TRC-382) 是一种特别增强了抗癌活性的Phenothiazine 化合物,对EGFR驱动的癌症异种移植模型表现出显著的效果。其作用机制归因于同时抑制PI3K-AKT和RAS-ERK信号通路。 | |||
T39239 |
TRC-766
|
||
TRC-766, a negative control of RTC-5 (TRC-382), is a compound that exhibits protein phosphatase 2A (PP2A) binding properties while lacking phosphatase activation capabilities. |