Cat. No. | Product Name | Target | Signaling Pathways |
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T17149 |
Tr-PEG2-OH
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Others | Others |
Tr-PEG2-OH is a PEG-based PROTAC linker utilized in PROTAC synthesis[1]. It also serves as a non-cleavable 2-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[2]. | |||
T37173 |
MPro Inhibitor 11a
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MProinhibitor 11a is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.053 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.53 μM). MProinhibitor 11a also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM. 1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-... | |||
T82838 |
BODIPY TR-X
BODIPY TR-X NHS Ester |
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BODIPY TR-X (BODIPY TR-X NHS Ester) 为荧光染料,用于标定含伯胺 (R-NH2) 蛋白质、修饰有胺基的寡核苷酸及其他含胺结构。其与蛋白质或抗体结合后,展现鲜明的红色荧光(λex=545 nm,λem=560 nm)。 | |||
T81669 |
NKG2D-IN-2
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NKG2D-IN-2(化合物47)为NKG2D抑制剂,其IC50在NKG2D/MICA及ULBP6 TR-FRET测定中分别为0.1 µM与0.2 µM。 | |||
T37174 |
SARS-CoV MPro-IN-1
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MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 μM). MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM. 1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-C... |