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Search Results for " tnfrsf11b "

2

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T70061	CGP 71683 (free base)
	CGP 71683 (free base) is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
T5587	CGP71683 hydrochloride CGP71683A,盐酸CGP71683	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	CGP71683 hydrochloride (CGP71683A) 是竞争性的神经肽受体拮抗剂，Ki 值为 1.3 nM。

化合物

CGP 71683 (free base)

Cat.No: T70061

CGP71683 hydrochloride

Cat.No: T5587

Synonym: CGP71683A,盐酸CGP71683

Target: Neuropeptide Y Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) OPG,Tumor Necrosis Factor Receptor Superfamily Member 11...	Human	HEK293 Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-03323	Osteoprotegerin Protein, Rhesus, Recombinant (hFc) tumor necrosis factor receptor superfamily member 11b	Rhesus	HEK293 Cells
	Osteoprotegerin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is G7N005.
TMPJ-00253	OPG Protein, Mouse, Recombinant (His) Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhi...	Mouse	HEK293 Cells
	Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ...
TMPH-02264	TNFSF11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Induces osteoclastogenesis by activating multipl...

重组蛋白

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

Cat.No: TMPJ-01466

Species: Human

Expression System: HEK293 Cells

Osteoprotegerin Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03323

Species: Rhesus

Expression System: HEK293 Cells

OPG Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00253

Species: Mouse

Expression System: HEK293 Cells

TNFSF11 Protein, Human, Recombinant (His)

Cat.No: TMPH-02264

Species: Human

Expression System: HEK293 Cells

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