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Search Results for " tnf-r1 "

Targets Recommended: SARS-CoV

1

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T20033	Direct Violet 1 NSC75778,NSC 75778,Airedale Violet ND,NSC-75778,直接青莲N,Direct Violet N,CCRIS 2413	SARS-CoV	Microbiology/Virology
	Direct Violet 1 (CCRIS 2413) 是一种偶氮染料，是纺织品染料，也是 SARS-CoV-2 刺突蛋白和 ACE2 抑制剂之间的蛋白质相互作用，IC50为 1.47-2.63 µM。

化合物

Direct Violet 1

Cat.No: T20033

Synonym: NSC75778,NSC 75778,Airedale Violet ND,NSC-75778,直接青莲N,Direct Violet N,CCRIS 2413

Target: SARS-CoV

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02535	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) TNFalpha-R1,TNFAR,TNF-R-...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118.
TMPY-01639	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) TNFalpha-R1,TNFRp55,CD120a,TN...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118.
TMPK-00564	TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) TBP1,TNF-RI,TNFAR,p55,p60,p55-R,TNF	Cynomolgus	HEK293 Cells
	Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.
TMPJ-00280	TNF R1 Protein, Mouse, Recombinant Tnfrsf1a,Tumor necrosis factor receptor superfamily...	Mouse	E. coli
	Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the...
TMPJ-00655	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His） TRAIL-R1,TNFRSF10A,cytotoxic TRAIL recepto...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant TNF-a,Tumor Necrosis Factor,TNF-α,TNF<...	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ...
TMPH-02876	RIPK1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold functions regulating inflammatory signaling and cell survival. Has kinase-independent scaffold functions: upon binding of TNF to TNFR1, RIPK1 is recruited to the TNF-R1 signaling complex (TNF-RSC also known as complex I) where it acts as a scaffold protein promoting cell survival, i...
TMPY-01176	cIAP1 Protein, Human, Recombinant (Avi) Hiap-2,API1,HIAP2,RNF48,baculoviral IAP repeat containing 2,...	Human	E. coli
	The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP repeats (BIRs). The BIR domains of cIAP1 and cIAP2 bind to caspases, the key effector proteases of apoptosis. The IAP protein family which can enhance cell survival are crucial regulators of programmed cell death. Both cIAP1 and cIAP2 are the E3 ubiquitin protein isopeptide ligase...

重组蛋白

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02535

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01639

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00564

Species: Cynomolgus

Expression System: HEK293 Cells

TNF R1 Protein, Mouse, Recombinant

Cat.No: TMPJ-00280

Species: Mouse

Expression System: E. coli

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His）

Cat.No: TMPJ-00655

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Rabbit, Recombinant

Cat.No: TMPJ-00779

Species: Rabbit

Expression System: E. coli

RIPK1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02876

Species: Mouse

Expression System: E. coli

cIAP1 Protein, Human, Recombinant (Avi)

Cat.No: TMPY-01176

Species: Human

Expression System: E. coli

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