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Cat. No. Product Name Target Signaling Pathways
T10630 BuChE-IN-TM-10

TM-10

AChR Neuroscience
BuChE-IN-TM-10 (TM-10) 是一种有效的丁基胆碱酯酶 (BuChE) 抑制剂,其IC50 值为8.9 nM。BuChE inhibitor 1能够抑制和分解自诱导的Aβ聚合, 表现出强大的抗氧化活性和良好的血脑屏障 (BBB) 渗透性。可用于阿尔兹海默症的研究。
T71908 NU1085

NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer). Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.

化合物

BuChE-IN-TM-10
Cat.No: T10630
Synonym: TM-10
Target: AChR
NU1085
Cat.No: T71908
Synonym:
Target:
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