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10

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T28982	TLC 388 TLC-388,TLC388
	TLC 388, a DNA topoisomerase I inhibitor, is used potentially for the treatment of Renal carcinoma and Hepatocellular carcinoma
T9847	TLC2976-0103
	ROCK1-IN-1 是一种ROCK1抑制剂，Ki 值为 540 nM。ROCK1-IN-1 可用于高血压、青光眼、勃起功能障碍的研究。
T121011	TLC1566-0618	STAT	JAK/STAT signaling; Stem Cells
	TLC1566-0618 显示抗肿瘤活性并靶向stat。
T116837	TLC9995-0188
	Tyrosine-protein kinase ABL, IC50: 1500 nM
T116970	TLC3407-3786
	MMV665916 是一种喹唑啉二酮衍生物，是一种抗疟药。MMV665916 对恶性疟原虫 FcB1 菌株具有显著的抗疟原虫生长抑制活性，EC50值为 0.4 μM，并呈现出高选择性指数 (SI>250)。
T118496	TLC0873-0006
	Tyrosine-protein kinase FYN, Kd: 240 nM
TP1501L	CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)	MMP	Proteases/Proteasome
	CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base) 是基质金属蛋白酶 (MMP)-2 和 MMP-9 的抑制剂。它也被称为IV 型胶原酶或明胶酶。明胶酶是癌症治疗干预的潜在靶点，这些酶的抑制剂可以防止肿瘤进展。
TP1501	CTTHWGFTLC, CYCLIC
	This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of t
T76017	CTTHWGFTLC, CYCLIC TFA
	CTTHWGFTLC, CYCLIC TFA 是一种基质金属蛋白酶 MMP-2和MMP-9的环肽抑制剂。对MMP-9的IC50约为 8 μM。
T31172	DA 3505 DA-3505,DA3505
	DA 3505 is one of feprazone metabolite. Limits of detection are 0.1 microgram feprazone per ml plasma and 0.2 microgram of its metabolite per ml plasma using the HPLC method. Concentration down to about 0.5 microgram/ml plasma of both compounds can be det

化合物

Cat.No: T28982

Synonym: TLC-388,TLC388

Cat.No: T9847

Cat.No: T121011

Target: STAT

Cat.No: T116837

Cat.No: T116970

Cat.No: T118496

CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)

Cat.No: TP1501L

Target: MMP

CTTHWGFTLC, CYCLIC

Cat.No: TP1501

CTTHWGFTLC, CYCLIC TFA

Cat.No: T76017

Cat.No: T31172

Synonym: DA-3505,DA3505

Cat. No.	Product Name	Target	Signaling Pathways
T18927	Br-Mmc 4-Bromomethyl-7-methoxycoumarin,4-溴甲基-7-甲氧基香豆素	Others	Others
	Br-Mmc (4-Bromomethyl-7-methoxycoumarin) 常用于荧光标记，可测定含有羧基的化合物。它能够利用 TLC 或 HPLC 测定脂肪酸含量。

天然产物

Cat.No: T18927

Synonym: 4-Bromomethyl-7-methoxycoumarin,4-溴甲基-7-甲氧基香豆素

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01679	LCN1 Protein, Human, Recombinant (His) TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA	Human	HEK293 Cells
	Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo...
TMPH-02079	SPTLC2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb...
TMPH-02206	TLCD1 Protein, Human, Recombinant (His)	Human	E. coli
	Regulates the composition and fluidity of the plasma membrane. Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity. Does not appear to have any effect on LCPUFA synthesis. TLCD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is Q96CP7.

重组蛋白

LCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01679

Species: Human

Expression System: HEK293 Cells

SPTLC2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02079

Species: Human

Expression System: E. coli

TLCD1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02206

Species: Human

Expression System: E. coli

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