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Cat. No.	Product Name	Target	Signaling Pathways
T7296	THZ2 CDK7-IN-1	CDK	Cell Cycle/Checkpoint
	THZ2 (CDK7-IN-1) 是 THZ1 的类似物，是一种有效的选择性 CDK7 抑制剂，IC50值为 13.9 nM。它有治疗三阴性乳腺癌的潜力。
T39459	THZ-P1-2 THZ-P1-2
	THZ-P1-2 is a novel, specific inhibitor of PI5P4K that effectively targets PI5P4Kα. With an IC 50 of 190 nM, THZ-P1-2 selectively inhibits PI5P4Kα by forming covalent bonds with cysteine residues located on a disordered loop present in PI5P4Kα/β/γ. This mechanism not only disrupts autophagy but also elevates TFEB signaling. Moreover, THZ-P1-2 exhibits potent anticancer effects in leukemia cell lines, making it a promising candidate for therapeutic applications.