Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13104 |
TD-106
|
Others | Others |
TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation. | |||
T13105 | TD-428 | Epigenetic Reader Domain | Chromatin/Epigenetic |
TD-428 is a highly specific degrader of BRD4(DC50 of 0.32 nM). TD-428 is a BET PROTAC, which comprises TD-106 (a CRBN ligand) linked to JQ1 (a BET inhibitor). TD-428 efficiently induce BET protein degradation. |