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Cat. No. Product Name Target Signaling Pathways
T5361 T-26c

MMP Proteases/Proteasome
T-26c 是高效的、选择性的基质金属蛋白酶-13 抑制剂,IC50=6.75 pM。
T37860 T 26c disodium salt

Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable. Nara et al (2014) Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1 binding site. Bioorg.Med.Chem. 22 5487 PMID:25192810"
T5381 A-893

A-893 是一个具有细胞活性的,甲基转移酶SMYD2的抑制剂,IC50值为 2.8 nM。

化合物

T-26c
Cat.No: T5361
Synonym:
Target: MMP
T 26c disodium salt
Cat.No: T37860
Synonym:
Target:
A-893
Cat.No: T5381
Synonym:
Target:
TargetMol Loading
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