Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0280 |
Spiperone
螺哌隆,Spiroperidol,Spiropitan |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Spiperone (Spiropitan) 是多巴胺 D2、血清素5-HT1A 和血清素5-HT2A 拮抗剂。它是广泛使用的药理学工具。它具有研究神经系统疾病的潜力。 | |||
T23381 | Spiperone hydrochloride | Others | Others |
5-HT2A serotonin and selective D2-like dopamine receptor antagonist | |||
T22505 |
3'-Fluorobenzylspiperone maleate
|
Others | Others |
ligand for the D2 receptor | |||
T25432 |
Fluspiperone
NSC 354855,NSC354855,NSC-354855,R-28930,R 28930 |
||
Fluspiperone is an antipsychotic agent. | |||
T69449 | Cyclindole | ||
Cyclindole is an antipsychotic with a tricyclic structure that was never marketed. It displaces spiperone binding in vitro and elevates dopamine levels in the striatum, indicating it acts as a D₂ receptor antagonist. | |||
T71590 | AHR-5645B fumarate | ||
AHR-5645B fumarate is a substituted benzamide that has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes. | |||
T69174 | AHR-5645B free base | ||
AHR-5645B free base is a substituted benzamide which has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes. | |||
T38145 | Eltoprazine | ||
Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.IC50 value:Target: 5-HT1A/1B agonist; 5-HT2C antagonistin vitro: The binding of [3H]eltoprazine to whole tissue sections was saturable and revealed an apparent dissociation constant (Kd) of 11 nM. Specific [3H]eltoprazine binding was completely displaced by 5-HT; conversely, unlabelled eltoprazine reduced [3H]5-HT binding to the levels of no... |