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Cat. No. Product Name Target Signaling Pathways
T9992 SphK1&2-IN-1

S1P Receptor GPCR/G Protein
SphK1&2-IN-1 是一种鞘氨醇激酶抑制剂,具有抗炎、抗肿瘤和止血作用。
T70900 VT-ME6

VT-ME6 is a potent and selective sphingosine kinase 2 inhibitor. VT-ME6, contained a quaternary ammonium group as a warhead and established that a positively charged moiety is necessary for engaging key amino acid residues in the enzyme binding pocket.13,14 This compound is moderately potent (Ki = 8 lM) and displays three-fold selectivity for SphK2 over SphK1. Sphingosine-1-phosphate (S1P) is a ubiquitous, endogenous small molecule that is synthesized by two isoforms of sphingosine kinase (SphK...

化合物

SphK1&2-IN-1
Cat.No: T9992
Synonym:
Target: S1P Receptor
VT-ME6
Cat.No: T70900
Synonym:
Target:
TargetMol Loading
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