Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38611 |
Seco-DUBA
|
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Seco-DUBA, a duocarmycin (DUBA) prodrug, possess two hydroxyl groups suitable for antibody coupling through a linker. This compound, serving as a precursor, enables the synthesis of antibody-drug conjugates (ADCs). | |||
T39213 |
Seco-DUBA hydrochloride
|
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Seco-DUBA hydrochloride is a toxin for ADC drug SYD985. | |||
T18362 |
Vc-seco-DUBA
|
Others | Others |
Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1]. | |||
T82577 |
Desmethyl Vc-seco-DUBA
|
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Desmethyl Vc-seco-DUBA 是由可降解的ADC linker(Desmethyl Vc-seco)和DNA烷化剂DUBA构成,适用于ADC的合成。 | |||
T77905 |
Vobramitamab
AEX-4089 |
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Vobramitamab为针对人源B7-H3的单克隆抗体(mAb)。该抗体通过一个可切割的连接物与前药seco-DUBA相结合,构成一种抗体-药物偶联物(ADC)名为MGC018。 |