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Cat. No. Product Name Target Signaling Pathways
T4527 Seclidemstat

SP-2577

Histone Demethylase Chromatin/Epigenetic
Seclidemstat (SP-2577) 是非竞争性可逆KDM1A (LSD1)抑制剂,可用于尤文肉瘤的研究。它促进 SWI/SNF 复合物突变卵巢癌的抗肿瘤免疫,并抑制病毒产生、病毒 DNA 复制和晚期基因表达。
T39439 Seclidemstat mesylate

SP-2577 mesylate

Seclidemstat mesylate (SP-2577) is a highly effective and reversible inhibitor of KDM1A (LSD1), with a Ki of 31 nM and an IC 50 of 13 nM. It demonstrates significant potential in promoting antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, while also exhibiting inhibitory effects on virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate is a valuable tool for studying Ewing Sarcoma in research settings.

化合物

Seclidemstat
Cat.No: T4527
Synonym: SP-2577
Target: Histone Demethylase
Seclidemstat mesylate
Cat.No: T39439
Synonym: SP-2577 mesylate
Target:
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