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Search Results for " sapacitabine "

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0245	Sapacitabine CS682,CYC682	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T13621	CNDAC hydrochloride	Nucleoside Antimetabolite/Analog; Others; Drug Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	CNDAC hydrochloride 是一种核苷类似物，是沙帕他滨的代谢物。
T13621L	CNDAC	Others	Others
	CNDAC, a nucleoside analog, is a major metabolite of oral drug sapacitabine.
T71549	RKS-262
	RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line assay RKS262 exhibited significant cytotoxicity in ovarian cancer cells and a variety of other cell lines exceeding effects of commercial drugs such as cisplatin, 5-FU, cyclophosphamide or sapacitabine. Various leukemia cell-lines were most sensitive (GI(50): ~ 10 nM) while several...