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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79528 | SWS1 | PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
SWS1为d-(+)-生物素缀合的PD-L1抑制剂(IC50: 1.8 nM),显示出抗癌潜力。该化合物能提高肿瘤浸润淋巴细胞数量,并在B16-F10小鼠模型中展现抗肿瘤效果(TGI=66.1%)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00991 |
LIFR Protein, Human, Recombinant (His)
STWS,CD118,SJS2,LIF-R,leukemia inhibitory factor receptor al... |
Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1. | |||
TMPY-05493 |
LIFR Protein, Human, Recombinant (hFc)
LIF-R,CD118,leukemia inhibitory factor receptor alpha,SW... |
Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 116.1 kDa and the accession number is P42702-1. | |||
TMPY-06010 |
LIFR Protein, Human, Recombinant (His), Biotinylated
LIF-R,leukemia inhibitory factor receptor α,SJS2,leukemia in... |
Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1. | |||
TMPJ-01179 |
SWSAP1 Protein, Human, Recombinant (His)
SWS1-associated protein 1,SWIM-type zinc finger 7-a... |
Human | E. coli |
SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD51C, RAD51D and XRCC3. It involves in homologous recombination repair. ATPase is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). SWSAP1 has a DNA-binding activity which is independent of its ATPase activity. |