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Targets Recommended: PD-1/PD-L1

1

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T79528 SWS1

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
SWS1为d-(+)-生物素缀合的PD-L1抑制剂(IC50: 1.8 nM),显示出抗癌潜力。该化合物能提高肿瘤浸润淋巴细胞数量,并在B16-F10小鼠模型中展现抗肿瘤效果(TGI=66.1%)。

化合物

SWS1
Cat.No: T79528
Synonym:
Target: PD-1/PD-L1
Cat. No. Product Name Species Expression System
TMPY-00991 LIFR Protein, Human, Recombinant (His)

STWS,CD118,SJS2,LIF-R,leukemia inhibitory factor receptor al...

Human HEK293 Cells
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1.
TMPY-05493 LIFR Protein, Human, Recombinant (hFc)

LIF-R,CD118,leukemia inhibitory factor receptor alpha,SW...

Human HEK293 Cells
LIFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 116.1 kDa and the accession number is P42702-1.
TMPY-06010 LIFR Protein, Human, Recombinant (His), Biotinylated

LIF-R,leukemia inhibitory factor receptor α,SJS2,leukemia in...

Human HEK293 Cells
LIFR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1.
TMPJ-01179 SWSAP1 Protein, Human, Recombinant (His)

SWS1-associated protein 1,SWIM-type zinc finger 7-a...

Human E. coli
SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD51C, RAD51D and XRCC3. It involves in homologous recombination repair. ATPase is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). SWSAP1 has a DNA-binding activity which is independent of its ATPase activity.

重组蛋白

LIFR Protein, Human, Recombinant (His)
Cat.No: TMPY-00991
Species: Human
Expression System: HEK293 Cells
LIFR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05493
Species: Human
Expression System: HEK293 Cells
LIFR Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-06010
Species: Human
Expression System: HEK293 Cells
SWSAP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01179
Species: Human
Expression System: E. coli
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