Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17026 |
Tecovirimat
ST-246,特考韦瑞 |
Cysteine Protease | Proteases/Proteasome |
Tecovirimat 是一种核心蛋白半胱氨酸蛋白酶抑制剂,可能用于治疗天花感染。Tecovirimat 是一种新型抗病毒药物,对多种正痘病毒具有有效和选择性的活性(EC50:约 10 nM)。通过靶向病毒 p37 蛋白直系同源物来抑制正痘病毒的排出。迄今为止,Tecovirimat 已在所有小动物和非人类灵长类动物预防和治疗痘病毒引起的疾病模型中显示出功效。 | |||
T17026L |
Tecovirimat hydrate
ST246,ST 246,ST-246,SIGA 246,SIGA246,SIGA-246 |
||
Tecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to | |||
T70690 |
UAWJ246
|
||
UAWJ246 is a SARS-CoV-2 Protease inhibitor (IC50 = 45 nM). UAWJ246 provides new directions for the development of Mpro inhibitors as SARS-CoV-2 antivirals. |