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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39924 |
NF-κΒ activator 2
|
NF-κB | NF-κB |
NF-κΒ activator 2 是口服有效的 NF-ҡB 激活剂,EC50为 1.58 μM。它通过增加 NF-κB 的表达和激活来诱导 SOD2。它具有用于研究肌萎缩性侧索硬化症的价值。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00105 |
SOD2 Protein, Human, Recombinant (His)
Superoxide Dismutase [Mn] Mitochondrial,SOD2 |
Human | HEK293 Cells |
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential ... | |||
TMPJ-00104 |
SOD2 Protein, Human, Recombinant (E. coli, His)
SOD2,Superoxide Dismutase [Mn] Mitochondri... |
Human | E. coli |
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron dis... | |||
TMPY-02044 |
SOD2 Protein, Human, Recombinant
superoxide dismutase 2, mitochondrial,IPOB,MNSO... |
Human | E. coli |
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mitochondrial superoxide dismutase [SOD; manganese SOD (MnSOD) or SOD2] neutralizes highly reactive superoxide radical (O•-2), the first member in the plethora of mitochondrial reactive oxygen species. |