Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40121 |
SHP2-D26
SHP2-D26 |
PROTACs | PROTAC |
SHP2-D26 is a highly potent and effective SHP2 degrader. Its mechanism of action involves the induction of SHP2 degradation through binding to VHL-1 and SHP2 proteins. Additionally, the degradation of SHP2 induced by SHP2-D26 is dependent on neddylation and proteasome activity. | |||
T74430 |
SHP2 protein degrader-2
|
PROTACs | PROTAC |
SHP2protein degrader-2 (SHP2-D26) 是一种SHP2蛋白PROTAC 降解剂。SHP2protein degrader-2 可降低各种癌细胞中SHP2的表达水平。 |