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Targets Recommended: SGK Influenza Virus

3

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2622 GSK 650394

GSK650394

SGK; Influenza Virus Metabolism; Microbiology/Virology
GSK 650394 是一种新颖的 SGK 抑制剂,可抑制流感病毒复制。它还是一种血清和糖皮质激素调节的激酶 1 抑制剂。
T71947 SGK1 inhibitor

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.
T82385 FMF-06-098-1

PROTACs PROTAC
FMF-06-098-1是一种多靶点蛋白降解剂。通过专一性降解作用,FMF-06-098-1针对多种激酶,能够有效降解AAK1, ABL2, AURKA, AURKB, BUB1B, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDK6, CDK7, CDK9, CHEK1, CSNK1D, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1及WEE1等关键蛋白。

化合物

GSK 650394
Cat.No: T2622
Synonym: GSK650394
Target: SGK, Influenza Virus
SGK1 inhibitor
Cat.No: T71947
Synonym:
Target:
FMF-06-098-1
Cat.No: T82385
Synonym:
Target: PROTACs
Cat. No. Product Name Species Expression System
TMPY-04561 SGK3 Protein, Human, Recombinant (His & GST)

serum/glucocorticoid regulated kinase family, member 3,S...

Human Baculovirus Insect Cells
Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase C-terminal domain, one protein kinase domain and one PX (phox homology) domain. Two specific sites of SGK3, one in the kinase domain (Thr-32) and the other in the C-terminal regulatory region (Ser-486...

重组蛋白

SGK3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04561
Species: Human
Expression System: Baculovirus Insect Cells
TargetMol Loading
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