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Cat. No. Product Name Species Expression System
TMPJ-01349 SEMA4B Protein, Human, Recombinant (His)

SEMAC and SEMA4B,KIAA1745,Sem...

Human HEK293 Cells
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
TMPJ-01348 SEMA4B Protein, Human, Recombinant (hFc & His)

SEMAC,Semaphorin-4B,KIAA1745,...

Human HEK293 Cells
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for gr...
TMPK-01034 SEMA4B Protein, Mouse, Recombinant (His)

SEMA4B,SemC,Semaphorin-C,MGC13183...

Mouse HEK293 Cells
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.

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SEMA4B Protein, Human, Recombinant (His)
Cat.No: TMPJ-01349
Species: Human
Expression System: HEK293 Cells
SEMA4B Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01348
Species: Human
Expression System: HEK293 Cells
SEMA4B Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01034
Species: Mouse
Expression System: HEK293 Cells
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